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Basic information

CohesinDB ID: CDBP00420195

Locus: chr21-41939422-41940001

Data sourse: GSE206145, GSE111913, GSE67783, GSE86191

Cell type: RPE, RT-112, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 96% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 42%, "15_Quies": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, POU2F2, MYCN, TOP2A, PAF1, ZFX, XBP1, ZBTB48, WT1, TET2, YY1, RELA, TARDBP, ATF3, MYC, SP140, CBFB, CDK8, AGO2, NCOA3, TEAD3, KDM5B, ESR1, ZNF334, CTCF, RBM22, BCL11A, SPI1, AR, HEXIM1, HSF1, MAZ, AATF, SMC3, STAG1

Target gene symbol (double-evidenced CRMs): MX1,C2CD2,ABCG1,UMODL1,HSF2BP,PRDM15

Function elements

Human SNPs: .

Number of somatic mutations (coding): 2

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000157601, ENSG00000141956, ENSG00000157617, ENSG00000177398, ENSG00000160179, ENSG00000160207,

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Deatailed information for cohesin site CDBP00420195