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Basic information

CohesinDB ID: CDBP00420197

Locus: chr21-41947046-41947327

Data sourse: GSE206145-NatGen2015, GSE120943, GSE98367

Cell type: Fibroblast, Monocytes, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 96% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 51%, "15_Quies": 33%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: SMC1A, MAFG, CEBPA, HDAC1, RUNX1T1, TOP2A, PAF1, ZFX, DUX4, ESR2, FOXA1, CDK9, ZNF596, ERG, RELA, HDGF, ZNF384, ATF3, MYC, SMARCA4, CHD7, TCF4, GABPA, GATA1, NFE2, CEBPG, CEBPB, ESRRA, TRIM28, BAP1, MYB, CEBPD, ESR1, CTCF, RBM22, MAFK, SPI1, BCL11A, HDAC2, RBM25, FLI1, GATAD2A, ZNF316

Target gene symbol (double-evidenced CRMs): C2CD2,PRDM15,HSF2BP,UMODL1,MX1,ABCG1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 7

Number of somatic mutations (non-coding): 6

Related genes and loops

Related gene: ENSG00000157601, ENSG00000141956, ENSG00000157617, ENSG00000177398, ENSG00000160179, ENSG00000160207,

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Deatailed information for cohesin site CDBP00420197