Browse_each

Basic information

CohesinDB ID: CDBP00420200

Locus: chr21-41951919-41960803

Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE104888, ENCSR230ZWH, GSE72082, ENCSR000BSB, ENCSR501LQA, GSE116868, ENCSR760NPX, ENCSR000EGW, ENCSR000BLY, GSE126634, GSE25021, ENCSR150EFU, GSE105028, GSE121355, GSE111537, GSE131606, ENCSR330ELC, ENCSR000EDW, GSE108869, ENCSR000BUC, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE115602, GSE143937, GSE165895, GSE67783, ENCSR000BKV, GSE86191, GSE138405, GSE93080, GSE76893, GSE101921, GSE206145-NatGen2015, GSE120943, GSE112028, GSE130135, ENCSR703TNG, GSE116344, GSE138105, GSE94872, ENCSR895JMI, GSE118494, ENCSR000EEG, ENCSR338DUC, GSE98367, ENCSR193NSH, ENCSR768DOX, ENCSR879KXD, ENCSR000BLS, ENCSR000EHW, GSE85526, ENCSR981FDC, ENCSR247LSH, GSE206145, ENCSR000EHX, ENCSR748MVX, ENCSR767DFK, ENCSR495WGO, GSE97394, ENCSR217ELF, ENCSR000BTQ, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, GSE131956, GSE110061, GSE129526, ENCSR000HPG, GSE111913, GSE155324, ENCSR054FKH, ENCSR537EFT, ENCSR000EDE, ENCSR153HNT, GSE68388, GSE83726, GSE126990, GSE50893, ENCSR000ECS, GSE38411

Cell type: RH4, GM10847, GM2610, SLK, GM19240, HSPC, Liver, HuCC-T1, B-cell, H9-hESC, GM2630, HMEC, Fibroblast, RPE, HEKn, Ishikawa, GM12890, HeLa-S3, GM2255, IMR-90, BCBL-1, K-562, GM18486, DKO, HFFc6, GM18526, H1-hESC, SNYDER, Monocytes, GM18505, MB157, Lymphoblast, GM12878, GM12891, GM2588, GBM39, SK-N-SH, GM19239, HeLa-Tet-On, GM19193, RT-112, HAP1, GM19099, HUES64, Macrophage, GM12892, MCF-7, Hela-Kyoto, HCT-116, MCF-10A, HEK293T, Hep-G2, A-549, HUVEC, HCAEC, GM19238, OCI-AML-3, GM18951

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 52% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.344

Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS,Intergenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: non-Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 96% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "7_Enh": 25%, "2_TssAFlnk": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RELA, CHD8, AHR, MYCN, SP140, ZBTB26, ZBTB48, WT1, ZNF770, MAZ, FOS, TFAP2C

Target gene symbol (double-evidenced CRMs): ZBTB21,UMODL1,C2CD2,PRDM15,ABCG1,BACE2,RSPH1,UBASH3A,SLC37A1

Function elements

Human SNPs: Total_testosterone_levels

Number of somatic mutations (coding): 25

Number of somatic mutations (non-coding): 54

Related genes and loops

Related gene: ENSG00000182240, ENSG00000141956, ENSG00000157617, ENSG00000173276, ENSG00000177398, ENSG00000160179, ENSG00000160185, ENSG00000160188, ENSG00000160190,

eachgene

Deatailed information for cohesin site CDBP00420200