- Basic information
- CohesinDB ID: CDBP00420206
- Locus: chr21-41977344-41977846
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Data sourse: ENCSR703TNG, GSE67783, GSE86191
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Cell type: MCF-7, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
96% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 79%,
"14_ReprPCWk": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: BCL6, BRD1, ZSCAN5D, MYCN, ZFX, ZBTB48, WT1, RELA, MYC, MCM3, SP140, ZNF143, TFAP2C, TP53, CTCF, GATA6, NOTCH3, MAZ, SMC3, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): C2CD2,UMODL1,PRDM15
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 6
- Related genes and loops
- Related gene:
ENSG00000141956,
ENSG00000157617,
ENSG00000177398,
- Related loop:
chr21:41200000-41225000~~chr21:41950000-41975000,
chr21:41600000-41625000~~chr21:41950000-41975000,
chr21:41600000-41625000~~chr21:41975000-42000000,
chr21:41650000-41675000~~chr21:41950000-41975000,
chr21:41850000-41875000~~chr21:41950000-41975000,
chr21:41875000-41900000~~chr21:41975000-42000000,
chr21:41950000-41975000~~chr21:42100000-42125000,
chr21:41950000-41975000~~chr21:42275000-42300000,
chr21:41950000-41975000~~chr21:42425000-42450000,
chr21:41950000-41975000~~chr21:42475000-42500000,
chr21:41973118-41974876~~chr21:42116725-42118346,
chr21:41973241-41974866~~chr21:42448856-42450964,
chr21:41975000-42000000~~chr21:42075000-42100000,