- Basic information
- CohesinDB ID: CDBP00420209
- Locus: chr21-41991035-41991464
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Data sourse: GSE86191
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Cell type: HCT-116
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
96% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"4_Tx": 74%,
"5_TxWk": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, ZSCAN5C, XBP1, FOXA1, LEO1, ATF3, NFIC, MORC2, PAX5, ZNF629, ELF1, TRIM28, ESR1, CTCF, TCF12, EP300, E2F6, SOX6, TEAD4, EED, POU2F2, CHD8, BRD1, MYCN, KDM4C, DUX4, ZBTB48, ZSCAN5A, STAT1, ZBTB21, MYC, ONECUT1, RAD21, GRHL3, GABPA, STAT3, DNMT3B, NR3C1, CEBPB, SRSF3, EZH2, GRHL2, HDAC2, GATA2, FLI1, NCOA2, RUNX1, LDB1, SIN3A, ZFX, TET2, CREBBP, PRPF4, NOTCH1, RUNX2, GATA4, ZNF184, ARNT, PBX4, DAXX, HMGB2, PRDM9, PBX3, SUPT5H, FOS, MED1, L3MBTL2, SETDB1, RBM22, GSPT2, ARID2, REST, SMC3, STAG1, MLLT1, PPARG, TBL1X, MTA3, FOXA2, PAF1, E2F8, ZNF600, WT1, ZBTB33, HOXB13, BCL3, YY1, RELA, NEUROD1, SP140, HIF1A, GATA3, TAL1, MAX, ZNF143, NCOA3, TCF7L2, NEUROG2, TP53, ZNF334, MYOD1, PHOX2B, AR, HSF1, BRD4, JUND, MAZ, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): C2CD2,ZBTB21,PRDM15,UMODL1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 328
- Number of somatic mutations (non-coding): 82
- Related genes and loops