- Basic information
- CohesinDB ID: CDBP00420216
- Locus: chr21-42016245-42016751
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Data sourse: ENCSR000BLD, ENCSR167MTG, GSE67783, GSE72082, GSE86191, GSE25021, GSE111913, GSE105028, GSE206145-NatGen2015, ENCSR000ECE, ENCSR703TNG, GSE145327, GSE94872, GSE97394
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Cell type: MCF-7, H1-hESC, Fibroblast, HCT-116, Hep-G2, HUVEC, HUES64, RT-112, HSPC, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.889
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
94% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 53%,
"14_ReprPCWk": 33%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, FOXO1, TRP47, BCL6, FOXA2, POU5F1, MYCN, NKX2-2, NFATC1, ZFX, ZBTB17, ZBTB48, ZSCAN5A, WT1, FOXA1, TET2, CBX8, ERG3, BCL3, YY1, RELA, TAF15, MYC, SMARCA4, RAD21, SP140, GRHL3, SKIL, ARNT, ATF2, APC, PAX5, PBX3, MAX, FOS, CBX2, PLAG1, TERF1, CREB1, ESR1, USF2, STAT5A, JUN, CTCF, USF1, SPI1, GSPT2, AR, EGR1, FOSL2, POU2F3, HSF1, RNF2, BRD4, TCF3, MAZ, HCFC1R1, SMC3, STAG1, AHR, EED
- Target gene symbol (double-evidenced CRMs): PRDM15,UMODL1,C2CD2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000141956,
ENSG00000157617,
ENSG00000177398,
- Related loop:
chr21:41875000-41900000~~chr21:42000000-42025000,
chr21:41877545-41880451~~chr21:42008763-42011946,
chr21:41952495-41953705~~chr21:42008731-42011959,
chr21:41957072-41959223~~chr21:42008838-42011899,
chr21:41957418-41959149~~chr21:42008452-42012075,
chr21:42000000-42025000~~chr21:42100000-42125000,
chr21:42008409-42012026~~chr21:42106683-42108941,
chr21:42008452-42012075~~chr21:42106648-42108930,
chr21:42008727-42012041~~chr21:42106936-42108928,
chr21:42008728-42012071~~chr21:42106883-42109087,
chr21:42008738-42011645~~chr21:42106897-42108988,
chr21:42008738-42011645~~chr21:42116715-42119049,
chr21:42008738-42012043~~chr21:42106900-42108919,
chr21:42008744-42011714~~chr21:42060877-42064978,
chr21:42008744-42011714~~chr21:42106670-42109262,
chr21:42008744-42011714~~chr21:42116454-42119047,