- Basic information
- CohesinDB ID: CDBP00420223
- Locus: chr21-42035231-42036340
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Data sourse: GSE67783, GSE86191, GSE111913, GSE206145, GSE206145-NatGen2015
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Cell type: RPE, Fibroblast, HCT-116, RT-112, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SA2,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
94% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 63%,
"14_ReprPCWk": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, FOXA2, MYCN, SOX13, ZFX, XBP1, GTF2B, WT1, ZBTB48, MAFF, FOXA1, TET2, KDM1A, RARA, NEUROD1, SP140, ARNT, GABPA, NRIP1, NCOA3, TEAD3, ZMYM3, ESR1, CTCF, SOX5, RBM25, ZNF146, MAZ, NCOA2, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): PDE9A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops