- Basic information
- CohesinDB ID: CDBP00420230
- Locus: chr21-42069730-42069902
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Data sourse: GSE62063
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Cell type: Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: NIPBL
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
94% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 43%,
"14_ReprPCWk": 38%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, PGR, SOX2, NME2, XBP1, FOXA1, SUZ12, ZFHX2, HDGF, ATF3, NFIC, RUNX3, CBFB, ZSCAN4, TP63, MAF, ZNF506, ELF1, ZNF573, ESR1, OCA2, CTCF, JUN, EP300, E4F1, MNT, E2F4, ZNF512B, TEAD4, TFAP2C, POU2F2, CHD8, BRD1, MYCN, ZNF263, TOP2A, ZBTB17, ZBTB48, ZSCAN5A, STAT1, SRF, DDX5, ERG2, HNF4G, ERG, OGG1, MYC, EZH1, SMARCA4, MCM5, RAD21, GRHL3, GABPA, ZNF8, STAT3, DNMT3B, NR3C1, KMT2A, CREB1, EZH2, ZHX2, SPI1, SSRP1, FLI1, RUNX1, BCL6, HDAC1, CRY1, SOX13, ZFX, TET2, CBX8, ERG3, ZNF18, ZBTB2, CREBBP, RUNX2, GATA4, ARNT, NRF1, ZNF48, PBX3, ETV6, CHD1, FOS, MED1, MYB, SCRT2, ZNF3, L3MBTL2, SREBF2, STAT5A, USF1, MAFK, BCL11A, HNRNPLL, TCF3, FOXP1, AATF, ZNF623, STAG1, NFATC3, TRP47, ZNF316, FOXA2, AGO1, RBBP5, EBF1, NFATC1, ZNF600, WT1, MAFF, BCL3, ZKSCAN1, YY1, RELA, TARDBP, ZNF148, BRG1, SP140, ZIC2, HIF1A, TCF4, OTX2, TAL1, MAX, ZNF143, PLAG1, CBX2, NCOA3, NR2F1, ZNF687, ZNF334, TBX21, BHLHE40, AR, PAX3-FOXO1, RXR, HEXIM1, HSF1, ZBTB26, RNF2, BRD4, SCRT1, CLOCK, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): SLC37A1,UMODL1,PRDM15,PKNOX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 2
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000141956,
ENSG00000177398,
ENSG00000160190,
ENSG00000160199,
- Related loop:
chr21:41600000-41625000~~chr21:42050000-42075000,
chr21:41850000-41875000~~chr21:42050000-42075000,
chr21:42008744-42011714~~chr21:42060877-42064978,
chr21:42050000-42075000~~chr21:42525000-42550000,
chr21:42050000-42075000~~chr21:42975000-43000000,
chr21:42050000-42075000~~chr21:43350000-43375000,
chr21:42050000-42075000~~chr21:44250000-44275000,
chr21:42060877-42064978~~chr21:42106670-42109262,
chr21:42062098-42064822~~chr21:42076418-42078634,