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Basic information

CohesinDB ID: CDBP00420245

Locus: chr21-42133171-42133790

Data sourse: GSE67783, ENCSR153HNT, GSE86191

Cell type: K-562, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 94% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 55%, "14_ReprPCWk": 36%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, LCORL, SOX2, MEIS2, XBP1, FOXA1, SUZ12, PBX2, ZBTB7B, HDGF, ZNF274, BMI1, CHD7, ZNF444, THRAP3, TEAD1, BCLAF1, TRIM28, ESR1, CTCF, E4F1, DPF2, SOX6, ZNF512B, ZNF776, PLRG1, EHMT2, YBX1, NANOG, MYCN, TOP2A, CTBP1, ZBTB1, ZBTB17, ZBTB48, MTA2, ZNF317, ZSCAN21, NONO, SRF, DDX5, ARID3A, MCM5, MYC, RFX1, GRHL3, FOXK2, ZNF8, PRDM14, IKZF1, RCOR1, HNRNPH1, ESRRA, CEBPB, CREB1, EZH2, ARHGAP35, GRHL2, HES1, SPI1, HDAC2, GATAD2B, ZIM3, SALL2, HDAC1, ZFX, ZNF747, ZNF473, CBX8, MCM2, ZNF384, NOTCH1, ARNT, NFIB, ZBTB10, ZNF48, SUPT5H, GMEB1, SCRT2, MLLT1, STAG1, ZNF207, MTA3, FOXA2, WT1, ZNF662, ZBTB33, HOXB13, ZKSCAN1, KDM1A, RELA, TARDBP, NEUROD1, ZNF148, MCM3, SP140, HIF1A, ZNF311, TAL1, ZNF143, ZNF592, NCOA3, ZNF544, ZNF791, ZNF687, PKNOX1, AR, TAF1, ZNF366, RNF2, SCRT1, MAZ, ZSCAN23, AHR

Target gene symbol (double-evidenced CRMs): UMODL1,BACE2,TMPRSS3,WDR4,UBASH3A,TMPRSS2,PDE9A,HSF2BP,FAM3B,RSPH1,SLC37A1,RRP1B,ABCG1,MX1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000182240, ENSG00000183844, ENSG00000157601, ENSG00000184012, ENSG00000177398, ENSG00000160179, ENSG00000160183, ENSG00000160185, ENSG00000160188, ENSG00000160190, ENSG00000160191, ENSG00000160193, ENSG00000160207, ENSG00000160208,

eachgene

Deatailed information for cohesin site CDBP00420245