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Basic information

CohesinDB ID: CDBP00420247

Locus: chr21-42136531-42136713

Data sourse: ENCSR703TNG, GSE25021, GSE72082

Cell type: MCF-7

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 94% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 58%, "14_ReprPCWk": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, PAX7, TRP47, POU2F2, MYCN, EBF1, TOP2A, ZFX, NME2, ZBTB48, WT1, FOXA1, TET2, CBX8, ERG, RELA, ZNF384, ATF3, MYC, MCM5, SMARCA4, THAP1, RAD21, SP140, GRHL3, ZIC2, GABPA, MAX, NRIP1, FOS, SUPT5H, DNMT3B, CBX2, ZNF467, NCOA3, ZNF121, SCRT2, ESR1, EBF3, CTCF, BCL11A, AR, GATA2, HSF1, RNF2, HNRNPLL, BRD4, SCRT1, MAZ, AATF, SMC3, STAG1, AHR

Target gene symbol (double-evidenced CRMs): WDR4,FAM3B,UMODL1,TMPRSS3,UBASH3A,MX1,ABCG1,BACE2,RRP1B,HSF2BP,SLC37A1,TMPRSS2,PDE9A,RSPH1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 4

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000182240, ENSG00000183844, ENSG00000157601, ENSG00000184012, ENSG00000177398, ENSG00000160179, ENSG00000160183, ENSG00000160185, ENSG00000160188, ENSG00000160190, ENSG00000160191, ENSG00000160193, ENSG00000160207, ENSG00000160208,

eachgene

Deatailed information for cohesin site CDBP00420247