Browse_each

Basic information

CohesinDB ID: CDBP00420254

Locus: chr21-42158837-42159271

Data sourse: GSE67783, ENCSR153HNT, GSE86191

Cell type: K-562, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 94% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 38%, "14_ReprPCWk": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, NFIA, TRIM25, ZNF426, NME2, FOXA1, RXRB, MLL4, KDM3A, ZBTB7B, HDGF, PAX5, TEAD1, ZNF121, OCA2, PITX3, ZNF577, E4F1, SOX5, PAX8, DEK, E2F4, ZNF528, ZNF555, KMT2B, GATAD2A, ZNF263, TOP2A, CTBP1, DUX4, STAT1, ZNF563, ERG, NFKB2, ZBTB8A, EZH1, SMARCA4, RFX1, ZNF8, ZNF398, RCOR1, NR2F6, CEBPB, HNRNPL, CREB1, GABPB1, KLF17, GATA2, FLI1, HCFC1, DRAP1, MXI1, NR2C2, RELB, HCFC1R1, RUNX1, CEBPA, NKX2-2, HDAC1, CRY1, ZNF654, TET2, TRIM22, SMARCC1, PRDM10, ZBTB2, TFDP1, ATF2, FOXM1, SMARCB1, PIAS1, SMAD1, NR1H2, EVI1, STAT5A, ARID2, ELL2, NFATC3, CBFA2T2, MEF2B, ZNF207, CHD2, SS18, NFATC1, ZSCAN16, WT1, MEF2C, NEUROD1, ZNF510, ZFP36, TCF4, ZNF311, BATF, MAF1, ZSCAN26, PLAG1, ZFP69B, KLF4, BCL11B, ZNF281, ZBTB6, EGR2, ELF3, RXR, EGLN2, ZNF366, HSF1, ZBTB26, ILF3, ZNF316, FOSL1, XBP1, ZNF101, PBX2, TSC22D4, ATF3, ZFP64, RUNX3, CBFB, TP63, ZSCAN4, MITF, ZNF467, JMJD1C, MAF, ELF1, ZNF573, RBM39, SNAI2, CTCF, JUN, MNT, LMO1, ZBTB20, DPF2, SIX5, IRF4, ZNF423, TFAP2C, RBPJ, YBX1, ZBTB17, ZBTB48, NONO, SRF, DDX5, NBN, ZNF329, PBX1, HOMEZ, RXRA, NKX3-1, PRDM14, MIER3, HNRNPH1, VDR, NR3C1, ESRRA, STAT5B, KMT2A, ZBTB11, ARHGAP35, GRHL2, EBF3, SMARCA5, THAP11, LDB1, AFF4, SOX13, POU4F2, ZNF770, NFIB, ARNT, ZNF48, PRDM9, PBX3, NCAPH2, HMGXB4, TEAD3, DIDO1, ZNF670, ZXDB, ZNF680, KLF9, SP1, BCL11A, TFAP2A, NKX2-5, ATF7, ASH2L, CTBP2, GLIS2, PRDM6, ZNF623, SMC3, MLLT1, STAG1, STAG2, ZNF394, TRP47, MTA3, EBF1, MAFF, ZNF580, ZKSCAN1, BCL3, KDM1A, ZNF266, BRG1, ZIC2, GATA3, TAL1, NRIP1, ZNF143, MTA1, CBX2, TP53, ZNF334, ZSCAN22, NFKB1, ZNF140, BRD2, TBX21, RB1, BRD4, JUND, ZSCAN23, PGR, ZNF697, SOX2, PATZ1, TFAP4, BMI1, ZNF444, MXD4, ZNF189, NFE2L2, ESR1, PRKDC, GTF2F1, GLIS1, POU2F2, ZSCAN5D, ZNF778, ZBTB1, ZSCAN5A, ERG2, SP4, TBP, HOXC5, OGG1, ETS1, MYC, NKX2-1, GABPA, STAT3, IKZF1, DNMT3B, SRSF3, YBX3, EZH2, SPI1, HDAC2, GATAD2B, ATM, NFYB, ZNF554, NCOA2, ETV5, BCL6, ERG3, CREBBP, ZNF35, RARA, TAF15, ZNF781, ZNF518A, SMAD4, CBFA2T3, CDK8, ZEB1, MAFK, HNF4A, REST, ARID1A, ZHX1, HNRNPLL, BCOR, FOXP1, AATF, ZNF34, PPARG, ZNF692, GTF2B, ZNF662, ZNF574, RELA, TARDBP, SKIL, MAX, GFI1B, ZNF791, TCF7L2, KDM5B, NR2F1, PKNOX1, MYOD1, AR, PAX3-FOXO1, HEXIM1, AHR, FOSL2, LCORL, MEIS2, SUZ12, ZNF28, ZFHX2, CTCFL, PRDM12, MECOM, ZNF629, BCLAF1, TRIM28, ETV1, USF2, TCF12, EP300, BAF155, ZNF512B, E2F1, SMC1, TEAD4, EHMT2, EED, CHD8, BRD1, MYCN, RUNX1T1, CDK7, ID3, ZNF205, GATAD1, ARID3A, ZNF300, ASCL1, MCM5, RAD21, GRHL3, XRCC5, ZNF614, NFE2, ZNF667, ZNF750, JMJD6, HES1, ZNF664, TFE3, IRF1, MRTFB, ZC3H11A, MYF5, SMC1A, CBX1, ZFX, ZNF534, SMAD3, TWIST1, NOTCH1, CDK6, OSR2, PBX4, NR2C1, SUPT5H, FOS, CHD1, MED1, ZNF558, MYB, SETDB1, KLF16, NIPBL, ZBTB7A, PHIP, TCF3, SKI, FOXA2, ZNF600, FOXF1, ZBTB33, CDK9, HOXB13, YY1, SP140, HIF1A, OTX2, GATA1, HAND2, TLE3, SP7, NCOA3, NR2F2, ZNF687, ZNF213, BHLHE40, NFKBIZ, ZBTB42, NOTCH3, CLOCK, MAZ, BRCA1

Target gene symbol (double-evidenced CRMs): ABCG1,UBASH3A,SLC37A1,WDR4,RSPH1,HSF2BP,TMPRSS3

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 6

Related genes and loops

Related gene: ENSG00000160179, ENSG00000160183, ENSG00000160185, ENSG00000160188, ENSG00000160190, ENSG00000160193, ENSG00000160207,

eachgene

Deatailed information for cohesin site CDBP00420254