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Basic information

CohesinDB ID: CDBP00420259

Locus: chr21-42172666-42173562

Data sourse: GSE67783, GSE111913, ENCSR153HNT, GSE86191

Cell type: K-562, RT-112, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 94% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 56%, "14_ReprPCWk": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, TRP47, POU2F2, BCL6, SMC1A, AGO1, MYCN, POU5F1, FOXA2, ZFX, XBP1, ZBTB48, WT1, TET2, ERG, YY1, RELA, OGG1, ATF3, MYC, AHR, THAP1, SP140, GRHL3, CBFB, MAF1, STAT3, TP63, ZNF143, DNMT3B, ZNF736, PLAG1, NR2F1, EZH2, ZNF3, ESR1, ZIM3, OCA2, BMPR1A, USF2, CTCF, SPI1, MNT, AR, MXD3, HEXIM1, HSF1, RNF2, BRD4, PHIP, CLOCK, MAZ, AATF, SMC3, NCOR2, STAG1, TFAP2C

Target gene symbol (double-evidenced CRMs): HSF2BP,UBASH3A,TMPRSS3,WDR4,RSPH1,SLC37A1,ABCG1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 5

Related genes and loops

Related gene: ENSG00000160179, ENSG00000160183, ENSG00000160185, ENSG00000160188, ENSG00000160190, ENSG00000160193, ENSG00000160207,

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Deatailed information for cohesin site CDBP00420259