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Basic information

CohesinDB ID: CDBP00420260

Locus: chr21-42173962-42174405

Data sourse: GSE50893, GSE67783

Cell type: GM10847, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 94% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 56%, "14_ReprPCWk": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: CBFA2T2, BCL6, POU2F2, FOXA2, NKX2-2, CBX3, EBF1, ZFX, CTBP1, XBP1, ASH1L, ERG3, ERG2, YY1, RELA, NFYC, JUNB, NEUROD1, MYC, TRIP13, SMARCA4, ARNT, ATF2, SMC3, NFYA, DPF1, MAX, SP2, ZNF143, FOS, MITF, PLAG1, PDX1, ZEB1, TEAD1, NCOA3, TCF7L2, L3MBTL2, ZNF334, USF2, CTCF, USF1, SP1, E4F1, BCL11A, BHLHE40, RBM25, ATF7, ZBTB26, RAD51, BRD4, MAZ, NFYB, STAG1, AHR

Target gene symbol (double-evidenced CRMs): RSPH1,SLC37A1,WDR4,UBASH3A,HSF2BP,TMPRSS3,ABCG1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000160179, ENSG00000160183, ENSG00000160185, ENSG00000160188, ENSG00000160190, ENSG00000160193, ENSG00000160207,

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Deatailed information for cohesin site CDBP00420260