- Basic information
- CohesinDB ID: CDBP00420266
- Locus: chr21-42192041-42192438
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Data sourse: GSE111913, GSE67783, GSE68388
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Cell type: RT-112, HSPC, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
94% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"7_Enh": 30%,
"15_Quies": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, XBP1, FOXA1, PBX2, ZFHX2, ZNF274, ATF3, NFIC, RUNX3, TP63, ZNF736, MAF, JMJD1C, KLF5, TEAD1, RBM39, SNAI2, KLF6, ESR1, OCA2, ZNF23, MED26, CTCF, JUN, EP300, PAX8, E2F6, E2F1, TEAD4, TFAP2C, GLIS1, POU2F2, BRD1, MYCN, ZNF263, ZBTB17, ZBTB48, ZSCAN5A, SRF, ERG2, ERG, OGG1, MYC, SMARCA4, RAD21, GRHL3, BATF3, APC, STAT3, RCOR1, ZNF750, CEBPB, STAT5B, KMT2A, CREB1, GRHL2, SPI1, GATA2, NR2C2, NCOA2, RUNX1, SMC1A, CEBPA, ZFX, SMAD3, ERG3, ZNF18, SMARCC1, CREBBP, ZNF384, ZNF35, RUNX2, ARNT, NRF1, PBX4, PRDM9, SMARCB1, FOS, MED1, MYB, SCRT2, ZNF3, L3MBTL2, SETDB1, USF1, BCL11A, NR4A1, REST, TCF3, AATF, SMC3, STAG1, MLLT1, TRP47, PPARG, CHD2, ZNF600, WT1, HOXB13, YY1, RELA, BRG1, SP140, ZIC2, HIF1A, TCF4, GATA3, BATF, TAL1, MAX, NRIP1, PLAG1, KLF4, BCL11B, NR2F1, TP53, ZNF334, MYOD1, EGR2, TBX21, AR, HSF1, RNF2, BRD4, SCRT1, CLOCK, MAZ, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 5
- Related genes and loops