- Basic information
- CohesinDB ID: CDBP00420285
- Locus: chr21-42247763-42247993
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Data sourse: GSE86191, GSE98367
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Cell type: HCT-116, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
94% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 31%,
"14_ReprPCWk": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, AR, MYC, MYCN, ZFX, HSF1, ARNT, DUX4, ZBTB48, WT1, TET2, MAZ, CTCF, SPI1
- Target gene symbol (double-evidenced CRMs): PRDM15,DNMT3L,SLC37A1,UMODL1,ABCG1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 5
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000141956,
ENSG00000177398,
ENSG00000160179,
ENSG00000160190,
ENSG00000142182,
- Related loop:
chr21:33200000-33225000~~chr21:42225000-42250000,
chr21:38225000-38250000~~chr21:42225000-42250000,
chr21:41425000-41450000~~chr21:42250000-42275000,
chr21:41500000-41525000~~chr21:42250000-42275000,
chr21:41850000-41875000~~chr21:42225000-42250000,
chr21:41925000-41950000~~chr21:42250000-42275000,
chr21:42125000-42150000~~chr21:42225000-42250000,
chr21:42125000-42150000~~chr21:42250000-42275000,
chr21:42150000-42175000~~chr21:42250000-42275000,
chr21:42225000-42250000~~chr21:42525000-42550000,
chr21:42225000-42250000~~chr21:43350000-43375000,
chr21:42225000-42250000~~chr21:44250000-44275000,