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Basic information

CohesinDB ID: CDBP00420297

Locus: chr21-42283471-42284076

Data sourse: GSE206145, GSE86191

Cell type: RPE, HCT-116

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 88% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "4_Tx": 32%, "5_TxWk": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, SOX2, NME2, XBP1, KDM4B, FOXA1, SUZ12, ZFHX2, TFAP4, ATF3, ZC3H8, CTCFL, ZBTB44, CHD7, CBFB, TP63, ZNF320, TEAD1, ELF1, ETV1, LMO2, ESR1, OCA2, JUN, CTCF, BAF155, KLF1, DPF2, E2F4, SMC1, TEAD4, PDX1, TFAP2C, GLIS1, POU2F2, BRD1, ZSCAN5D, MYCN, ZNF263, POU5F1, ID3, ZBTB48, ZSCAN5A, SRF, ERG2, ERG, OGG1, ETS1, MYC, ONECUT1, SMARCA4, RAD21, GRHL3, KLF12, STAT3, APC, NKX3-1, PRDM14, DNMT3B, NR3C1, SRSF3, CREB1, EZH2, KLF8, BMPR1A, GRHL2, SPI1, HDAC2, GATA2, FLI1, MRTFB, RUNX1, SMC1A, BCL6, CBX1, NKX2-2, SIRT6, ZFX, SMAD3, TET2, ERG3, CBX8, SMARCC1, RARA, ZNF384, ZBTB2, CREBBP, TAF15, RUNX2, FANCD2, ARNT, PRDM9, NCAPH2, CHD1, FOS, SMARCB1, TEAD3, ZEB1, KDM6B, SCRT2, PIAS1, ZNF3, NCOA1, SREBF2, USF1, HNF4A, REST, ARID1A, FOXP1, AATF, SMC3, STAG1, STAG2, TRP47, CBFA2T2, FOXA2, AGO1, EBF1, MTA3, SS18, ZNF600, WT1, CDK9, HOXB13, ZKSCAN1, KDM1A, YY1, RELA, KAT2B, BRG1, SP140, ZIC2, HIF1A, KLF15, TAL1, MAF1, MAX, NRIP1, ZNF143, CBX2, PLAG1, NR2F2, TCF7L2, NR2F1, KDM5B, TP53, ZNF334, ZSCAN22, NFKB1, EGR2, ELF3, AR, RXR, EGLN2, HEXIM1, EGR1, TFIIIC, HSF1, BRD4, SCRT1, MAZ, AHR

Target gene symbol (double-evidenced CRMs): PDE9A,TMPRSS2,UMODL1,PRDM15,UBASH3A,C2CD2,ABCG1,MX1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 48

Number of somatic mutations (non-coding): 8

Related genes and loops

Related gene: ENSG00000157601, ENSG00000184012, ENSG00000141956, ENSG00000157617, ENSG00000177398, ENSG00000160179, ENSG00000160185, ENSG00000160191,

eachgene

Deatailed information for cohesin site CDBP00420297