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Basic information

CohesinDB ID: CDBP00420311

Locus: chr21-42320786-42322135

Data sourse: GSE206145-GSE177045, GSE67783, ENCSR153HNT, GSE86191

Cell type: K-562, MCF-7, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: Mau2,SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 88% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 47%, "14_ReprPCWk": 37%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, SOX2, HMGN3, XBP1, FOXA1, RBFOX2, PBX2, ZFHX2, TFAP4, HDGF, LYL1, ATF3, ATF4, CBFB, MXD4, MECOM, PAX5, TP63, JMJD1C, INTS11, ELF1, TRIM28, BCLAF1, TEAD1, ETV1, LMO2, ESR1, MLL, CTCF, TCF12, JUN, EP300, KLF1, MNT, GATA6, DPF2, KMT2B, TFAP2C, RBPJ, GLIS1, POU2F2, BRD1, MYCN, ZNF263, RUNX1T1, ID3, POU5F1, CTBP1, ZBTB48, ZSCAN5A, STAT1, GATAD1, ERG2, ARID3A, ERG, PBX1, OGG1, ETS1, MYC, RAD21, GRHL3, NKX2-1, STAT3, XRCC5, PRDM14, IKZF1, NFE2, DNMT3B, NR3C1, CEBPB, ESRRA, SRSF3, KMT2A, CREB1, EZH2, BMPR1A, GRHL2, GABPB1, SPI1, GATA2, INTS13, MXD3, FLI1, HCFC1, NAB2, EP400, NCOA2, RUNX1, SMC1A, BCL6, CEBPA, CBX1, ZFX, TET2, ERG3, RARA, CREBBP, NOTCH1, ZBTB2, RUNX2, ARNT, ZNF48, PRDM9, SMAD4, CBFA2T3, ETV6, PBX3, FOS, CHD1, MED1, ZEB1, TEAD3, MYB, L3MBTL2, EVI1, BCL11A, SP1, NIPBL, NR4A1, ZBTB7A, ZNF605, TCF3, AATF, SMC3, STAG1, MLLT1, SKI, TRP47, CBFA2T2, AGO1, EBF1, SS18, WT1, ESR2, KDM1A, YY1, RELA, TARDBP, BRG1, SP140, ZFP36, TCF4, HIF1A, GATA3, TAL1, MAX, NRIP1, ZNF143, CEBPG, NCOA3, NR2F1, KDM5B, PKNOX1, ZNF334, EGR2, ELF3, BHLHE40, AR, ZBTB16, ZNF579, RXR, EGR1, HEXIM1, HSF1, BRD4, CLOCK, MAZ, AHR

Target gene symbol (double-evidenced CRMs): TMPRSS2,WDR4,UMODL1,PDE9A,SLC37A1,RSPH1,UBASH3A,TMPRSS3

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 5

Related genes and loops

Related gene: ENSG00000184012, ENSG00000177398, ENSG00000160183, ENSG00000160185, ENSG00000160188, ENSG00000160190, ENSG00000160191, ENSG00000160193,

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Deatailed information for cohesin site CDBP00420311