- Basic information
- CohesinDB ID: CDBP00420314
- Locus: chr21-42333883-42334046
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Data sourse: GSE120943, GSE98367
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Cell type: Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
88% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"14_ReprPCWk": 51%,
"15_Quies": 43%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF366, ZNF512, NCOR2, NME2
- Target gene symbol (double-evidenced CRMs): UBASH3A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 10
- Related genes and loops
- Related gene:
ENSG00000160185,
- Related loop:
chr21:42144411-42146838~~chr21:42336819-42339025,
chr21:42325000-42350000~~chr21:42425000-42450000,
chr21:42325000-42350000~~chr21:42800000-42825000,
chr21:42335706-42339182~~chr21:42437265-42438562,
chr21:42336547-42339124~~chr21:42448845-42450957,
chr21:42336747-42338965~~chr21:42448842-42450946,
chr21:42336807-42338774~~chr21:42449322-42450806,
chr21:42336819-42339025~~chr21:42448763-42451324,
chr21:42336829-42338858~~chr21:42448798-42450961,
chr21:42336832-42339100~~chr21:42448762-42450961,
chr21:42336860-42338813~~chr21:42449084-42450924,
chr21:42336860-42339221~~chr21:42448814-42450934,
chr21:42336947-42338996~~chr21:42449010-42450957,
chr21:42337150-42338850~~chr21:42449091-42451494,
chr21:42337183-42339009~~chr21:42448752-42450926,
chr21:42337200-42339002~~chr21:42448353-42451045,
chr21:42337222-42338891~~chr21:42449125-42450914,