- Basic information
- CohesinDB ID: CDBP00420328
- Locus: chr21-42390708-42391993
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Data sourse: GSE206145-GSE177045, GSE67783, GSE72082, GSE206145, ENCSR054FKH, ENCSR703TNG, ENCSR000ECS
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Cell type: MCF-7, Hep-G2, HeLa-S3, HSPC, B-cell
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: Mau2,SMC3,Rad21,SA1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
88% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 31%,
"15_Quies": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, HMG20A, FOXA1, RXRB, CDK2, CDX2, TEAD1, ZNF217, ESR1, OCA2, EP300, BAF155, MNT, SOX5, TEAD4, FOXA3, ZNF175, GATAD2A, TFAP2C, CTBP1, GATAD1, SAP130, ERG, MYC, RAD21, GRHL3, GABPA, ZNF614, MIER3, DNMT3B, NR2F6, VDR, NR3C1, GRHL2, TRPS1, HDAC2, GATA2, ZNF644, ZGPAT, NCOA2, THAP11, BCL6, CBX1, CEBPA, SIN3A, ZFX, SOX13, ZNF534, CREBBP, RARA, NFIB, PBX4, ARNT, ZNF48, SMAD4, FOXM1, TEAD3, U2AF1, HNF4A, IKZF5, ASH2L, CTBP2, FOXP1, FOXA2, ZNF207, SS18, ESR2, RELA, HIF1A, GATA3, MAX, NRIP1, TLE3, CEBPG, NCOA3, NR2F2, KAT8, ARID4B, AR, BHLHE40, YAP1, RXR, ZBTB26, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): TMPRSS3,UMODL1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 25
- Number of somatic mutations (non-coding): 5
- Related genes and loops