- Basic information
- CohesinDB ID: CDBP00420337
- Locus: chr21-42405775-42406562
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Data sourse: ENCSR153HNT, GSE86191
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Cell type: K-562, HCT-116
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
88% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 33%,
"14_ReprPCWk": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, HMG20A, SOX2, MEIS2, HMGN3, FOXA1, HLF, RBFOX2, PBX2, UBTF, ZFHX2, HDGF, ZNF274, ATF3, NFIC, ZNF362, THAP1, RUNX3, ATF4, CBFB, MECOM, SMARCE1, PAX5, MITF, ZNF320, MAF, RLF, JMJD1C, TEAD1, BCLAF1, ELF1, TRIM28, RBM39, NFE2L2, LMO2, ESR1, MLL, HDAC8, USF2, CTCF, SND1, TCF12, JUN, EP300, E4F1, LMO1, MNT, GATA6, ARID5B, DPF2, PAX8, E2F6, IRF4, TRIM24, SOX6, ZNF280A, TEAD4, KMT2B, ZNF175, GATAD2A, EHMT2, RBPJ, EED, TFAP2C, POU2F2, CHD8, MYCN, ZNF263, CDK7, ID3, RUNX1T1, CTBP1, MTA2, POU5F1, ZBTB48, DUX4, STAT1, ZSCAN5A, NONO, NBN, ARID3A, PHB2, ERG2, TBP, ERG, ZBTB21, PRDM9, ASCL1, MIER1, SMARCC2, ETS1, MYC, OGG1, SMARCA4, ZNF341, ARID1B, GRHL3, PROX1, NKX2-1, FOXK2, GABPA, STAT3, XRCC5, UBN1, IKZF1, RCOR1, LEF1, NR2F6, NFE2, ZNF639, HNRNPH1, NR3C1, CEBPB, ESRRA, SRSF3, STAT5B, HNRNPL, KMT2A, CREB1, TBL1XR1, EZH2, GABPB1, PHF8, ELF4, SPI1, HES1, HDAC2, GATA2, ZNF644, SIX2, FLI1, MXI1, RELB, ATF1, ETV5, CC2D1A, PTBP1, RUNX1, MAFG, BCL6, CEBPA, HDAC1, LDB1, SMC1A, SIN3A, ZFX, SOX13, SIRT6, SMAD3, ERG3, TRIM22, ZMIZ1, SMARCC1, PRDM10, NSD2, MEF2A, ZBTB2, ZNF384, NOTCH1, CREBBP, BRD9, RUNX2, CDK6, GATA4, ZNF184, ARNT, DAXX, NRF1, ATF2, ZNF48, ZNF518A, ZEB2, SMAD4, FOXM1, ETV6, ZNF10, FOS, CBFA2T3, CDK8, HMBOX1, SUPT5H, MED1, CHD1, GMEB1, TEAD3, PML, CEBPD, MYB, KDM6B, SMAD1, VEZF1, C11orf30, NCOA1, L3MBTL2, SETDB1, STAT5A, KLF16, MAFK, NIPBL, BCL11A, USF1, NR4A1, REST, ZBTB7A, CCNT2, ATF7, POU2F3, HNRNPLL, AFF1, BCOR, MBD2, AATF, SMC3, NCOR2, MLLT1, STAG1, NFATC3, TRP47, CBFA2T2, MEF2B, ZNF316, FOXA2, MTA3, EBF1, CREM, NFATC1, E2F8, CBX3, ZNF692, GTF2B, MAFF, RBBP5, MEIS1, WT1, ZNF574, MEF2C, TCF7, ZBTB33, ZNF580, BCL3, ZKSCAN1, KDM1A, YY1, RELA, CREB3L1, TARDBP, FOXO3, JUNB, NEUROD1, ZNF282, SP140, ZFP36, SKIL, TCF4, GATA3, BATF, TAL1, MAX, TOP2A, SPIB, GATA1, MTA1, ZNF143, PLAG1, CEBPG, ZNF592, BCL11B, GFI1B, NR2F2, ZKSCAN8, NCOA3, KLF4, NR2F1, TCF7L2, KDM5B, TP53, ZNF687, ZNF334, NFKB1, EGR2, TBX21, BHLHE40, AR, TAF1, ZBTB40, RXR, ZNF324, EGR1, HEXIM1, TFIIIC, HSF1, RNF2, IKZF2, BRD4, JUND, NCOR1, MYNN, ILF3, MAZ, ZBTB26, CUX1, CLOCK, ZNF24, AHR
- Target gene symbol (double-evidenced CRMs): UBASH3A,RSPH1,ABCG1,SLC37A1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 102
- Number of somatic mutations (non-coding): 0
- Related genes and loops