- Basic information
- CohesinDB ID: CDBP00420341
- Locus: chr21-42418387-42418668
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Data sourse: GSE67783, GSE86191
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Cell type: HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
88% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 46%,
"15_Quies": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, TRP47, CHD8, BRD1, TBL1X, MYCN, POU5F1, CBX1, CEBPA, ZFX, ZNF707, XBP1, TOP2A, ZBTB48, WT1, FOXA1, TET2, RELA, ATF3, MYC, ETS1, SP140, GRHL3, ARNT, MAX, SMARCB1, SNRNP70, HNRNPH1, MLLT1, GRHL2, SETDB1, CTCF, BRD4, AATF, HCFC1R1, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): RSPH1,UBASH3A,ABCG1,SLC37A1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 195
- Number of somatic mutations (non-coding): 65
- Related genes and loops
- Related gene:
ENSG00000160179,
ENSG00000160185,
ENSG00000160188,
ENSG00000160190,
- Related loop:
chr21:42300000-42325000~~chr21:42400000-42425000,
chr21:42392339-42394372~~chr21:42422767-42426562,
chr21:42392456-42394336~~chr21:42414406-42416483,
chr21:42392456-42394336~~chr21:42422709-42426547,
chr21:42400000-42425000~~chr21:42500000-42525000,
chr21:42400000-42425000~~chr21:42800000-42825000,