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Basic information

CohesinDB ID: CDBP00420343

Locus: chr21-42429069-42429373

Data sourse: GSE67783

Cell type: HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: SA1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 88% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "14_ReprPCWk": 37%, "15_Quies": 37%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, ZNF496, SOX2, FOXA1, TFAP4, ATF3, MXD4, SMARCE1, TEAD1, ESR1, MLL, CTCF, BAF155, MNT, SOX5, CREB3, E2F1, TEAD4, EHMT2, RBPJ, TFAP2C, GLIS1, BRD1, ZSCAN5D, MYCN, POU5F1, ZBTB48, ZSCAN5A, SAP130, ERG, MIER1, SMARCC2, MYC, SMARCA4, RAD21, GRHL3, STAT3, XRCC5, IKZF1, EZH2, GRHL2, SPI1, MIXL1, TFE3, GATA2, MXD3, RUNX1, CBX1, SIN3A, ZFX, TET2, ERG3, SMARCC1, CREBBP, RARA, ZNF48, FOS, SMARCB1, TEAD3, USF1, REST, POU2F3, ZNF548, AFF1, AATF, SMC3, STAG1, TRP47, ZNF316, TBL1X, FOXA2, PPARG, SS18, MIER2, WT1, CDK9, YY1, RELA, SP140, ZIC2, HIF1A, MAX, ZNF143, NCOA3, NR2F1, KDM5B, TP53, ZNF334, MYOD1, AR, RXR, EGLN2, ZBTB26, HSF1, BRD4, MAZ, AHR

Target gene symbol (double-evidenced CRMs): ABCG1,RIPK4,HSF2BP,TFF2,PRDM15,UMODL1,UBASH3A,C2CD2,SLC37A1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 6

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000183421, ENSG00000141956, ENSG00000157617, ENSG00000177398, ENSG00000160179, ENSG00000160181, ENSG00000160185, ENSG00000160190, ENSG00000160207,

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Deatailed information for cohesin site CDBP00420343