Browse_each

Basic information

CohesinDB ID: CDBP00420345

Locus: chr21-42432008-42432290

Data sourse: GSE25021, GSE67783, ENCSR153HNT

Cell type: K-562, MCF-7, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 88% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "9_Het": 31%, "15_Quies": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: POU2F2, CBX3, MYCN, ZSCAN5C, TOP2A, KDM4C, SS18, WT1, DUX4, ZNF214, FOXA1, KDM1A, CREBBP, ZNF626, MYC, SP140, HIF1A, GATA3, MAX, FOS, GATA1, TRIM28, ZMYM3, ZNF217, SETDB1, CTCF, AR, REST, E2F6, RBM25, ZNF280D, SMARCA5, MAZ, ZNF280A, STAG1, ZNF316

Target gene symbol (double-evidenced CRMs): RIPK4,TFF2,UBASH3A,C2CD2,SLC37A1,HSF2BP,PRDM15,ABCG1,UMODL1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 105

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000183421, ENSG00000141956, ENSG00000157617, ENSG00000177398, ENSG00000160179, ENSG00000160181, ENSG00000160185, ENSG00000160190, ENSG00000160207,

eachgene

Deatailed information for cohesin site CDBP00420345