Deatailed information for cohesin site CDBP00420358

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  • Basic information
  • CohesinDB ID: CDBP00420358
  • Locus: chr21-42468693-42469817
  • Data sourse: GSE38395, GSE93080, ENCSR000DZP, ENCSR230ZWH, GSE206145, GSE62063, GSE68388, GSE73207, GSE50893, ENCSR917QNE
  • Cell type: GM2610, Liver, HuCC-T1, B-cell, GM2630, GM12890, hLCL, GM2255, GM18486, GM18526, SNYDER, TF-1, GM12878, GM12891, GM2588, Ramos, GM12892, GM19238, GM18951
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 6% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.789
  • Subunit: NIPBL,SA1,Rad21,SMC1,Mau2,SMC3
  • CTCF binding site: non-CTCF CTCF motif: False
  • Genomic location: TES
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
  • Compartment: 88% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "15_Quies": 30%, "5_TxWk": 24%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, FOXA1, MLL4, HDGF, ZBTB44, IKZF3, PAX5, TEAD1, ZNF121, LMO2, ZNF561, ZNF528, KLF3, KMT2B, GATAD2A, JARID2, NANOG, BRD3, ZNF263, POU5F1, CTBP1, STAT1, ZNF488, ERG, ZNF597, ZBTB8A, NFKB2, SMARCA4, RFX1, RCOR1, CEBPB, CREB1, GATA2, ZNF644, MXD3, FLI1, HCFC1, RELB, RUNX1, CEBPA, NKX2-2, HDAC1, ZNF654, TRIM22, PRDM10, ZBTB2, ATF2, FOXM1, SP2, PML, TERF1, ZNF331, SMAD1, PIAS1, NR1H2, C11orf30, EVI1, STAT5A, MBD2, NFATC3, CBFA2T2, MEF2B, CBX3, CREM, NFATC1, SS18, ZSCAN16, WT1, MEF2C, NEUROD1, JUNB, TCF4, ZFP36, BATF, SPIB, PLAG1, KLF4, BCL11B, IRF5, ZBTB6, MED, EGR2, ELF3, ARID4B, RXR, EGLN2, ZBTB26, NCOR1, SCRT1, ILF3, FOSL1, HNF1A, PBX2, ATF3, ZFP64, RUNX3, CBFB, ZNF273, MITF, BACH2, ZNF467, MYOG, JMJD1C, RBM39, CTCF, JUN, DPF2, IRF4, ZNF423, PDX1, TFAP2C, RBPJ, MTA2, ZBTB17, ZBTB48, ZSCAN21, NONO, SRF, DDX5, NBN, CHD4, PBX1, RXRA, BATF3, NKX3-1, HNRNPH1, ESRRA, KMT2A, TBL1XR1, GRHL2, SMARCA5, NFIL3, LDB1, POU4F2, ZMIZ1, ZNF18, ARNT, DAXX, BACH1, ZEB2, HMBOX1, PBX3, MAFB, ETV6, DIDO1, ZXDB, USF1, BCL11A, SP1, ATF7, ASH2L, PRDM6, SMC3, MLLT1, STAG1, ZNF394, MTA3, EBF1, MEIS1, ZNF580, ZKSCAN1, BCL3, BRG1, GATA3, TAL1, ZNF143, TP53, ZSCAN22, NFKB1, PHOX2B, BRD2, TBX21, RB1, RNF2, IKZF2, BRD4, JUND, PGR, SOX2, PATZ1, UBTF, TFAP4, BMI1, ZNF189, SMARCE1, KLF6, NFE2L2, ZNF217, ESR1, TP73, KLF1, ZNF695, SOX9, SOX4, E2F6, GTF2F1, GLIS1, POU2F2, ZNF778, SP4, HNF4G, HOXC5, ETS1, MYC, ARID1B, NKX2-1, GABPA, STAT3, IKZF1, SPI1, HDAC2, INTS13, GATAD2B, ZNF554, ETV5, BCL6, SIN3A, ZBTB12, MEF2A, RARA, ZNF35, CREBBP, SMAD4, ZNF518A, CBFA2T3, CDK8, ZEB1, HNF4A, REST, ARID1A, HNRNPLL, BCOR, FOXP1, NCOR2, PPARG, ZNF44, ZNF692, GTF2B, ZNF30, ZNF574, RELA, TARDBP, SKIL, MAX, GFI1B, NEUROG2, NR2F1, KDM5B, TCF7L2, PKNOX1, MYOD1, AR, PAX3-FOXO1, ZNF324, AHR, ZSCAN5C, MEIS2, SUZ12, ZFHX2, ZNF90, NFIC, CTCFL, PRDM1, MECOM, CDX2, ZNF629, KLF5, BCLAF1, TRIM28, HNF1B, TCF12, EP300, BAF155, GATA6, PRDM4, SOX6, E2F1, SMC1, TEAD4, FOXA3, EED, MYCN, RUNX1T1, ID3, ARID3A, ZNF341, EOMES, RAD21, PROX1, XRCC5, NFE2, ZNF750, FEZF1, HES1, IRF1, HEXIM1-CDK9, ATF1, SMC1A, CBX1, MAFG, ZFX, SMAD3, IRF2, RUNX2, CDK6, GATA4, OSR2, ZNF184, SMAD2, PBX4, NRF1, NR2C1, FOS, MED1, CEBPD, MYB, SCRT2, ZNF3, L3MBTL2, KLF16, NIPBL, ZBTB7A, PHIP, TCF3, SKI, FOXA2, ZNF600, ZBED1, CDK9, HOXB13, YY1, HIF1A, GATA1, TLE3, SP7, NR2F2, ZNF512, ZNF687, ZNF843, BHLHE40, ZBTB42, MYNN, MAZ
  • Target gene symbol (double-evidenced CRMs): SLC37A1,ABCG1,RSPH1,UMODL1
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 0
  • Number of somatic mutations (non-coding): 11
  • Related genes and loops
  • Related gene: ENSG00000177398, ENSG00000160179, ENSG00000160188, ENSG00000160190,
  • Related loop: chr21:41600000-41625000~~chr21:42450000-42475000, chr21:42125000-42150000~~chr21:42450000-42475000, chr21:42150000-42175000~~chr21:42450000-42475000, chr21:42300000-42325000~~chr21:42450000-42475000, chr21:42450000-42475000~~chr21:42550000-42575000, chr21:42466723-42468288~~chr21:42517954-42519108, chr21:42466723-42468288~~chr21:42536785-42538249, chr21:42466738-42468349~~chr21:42512702-42515312, chr21:42466738-42468349~~chr21:42536098-42538505, chr21:42466750-42468364~~chr21:42534380-42538530, chr21:42466752-42469410~~chr21:42536796-42538220, chr21:42466778-42468284~~chr21:42536154-42538496, chr21:42466880-42468218~~chr21:42535463-42538505, chr21:42473977-42475276~~chr21:42512630-42515252,
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