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Basic information

CohesinDB ID: CDBP00420360

Locus: chr21-42471137-42471564

Data sourse: GSE67783, ENCSR153HNT, GSE86191

Cell type: K-562, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 88% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 40%, "5_TxWk": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: TRP47, BCL6, FOXA2, MYCN, CHD2, MEIS1, ZFX, XBP1, WT1, ZSCAN5A, ZBTB48, FOXA1, TET2, ERG3, ZNF770, ERG2, ZFHX2, KDM1A, ZNF90, MYC, RUNX2, BRG1, SMARCA4, SP140, ZIC2, TCF4, GRHL3, ARNT, BHLHE22, MAX, ZNF143, FOS, PLAG1, ZNF573, CCAR2, OCA2, EGR2, CTCF, E2F6, HEXIM1, POU2F3, RNF2, BRD4, TCF3, MAZ, AATF, STAG1

Target gene symbol (double-evidenced CRMs): UMODL1,SLC37A1,ABCG1,RSPH1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 5

Related genes and loops

Related gene: ENSG00000177398, ENSG00000160179, ENSG00000160188, ENSG00000160190,

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Deatailed information for cohesin site CDBP00420360