- Basic information
- CohesinDB ID: CDBP00420361
- Locus: chr21-42471844-42472360
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Data sourse: GSE67783, ENCSR153HNT, GSE86191
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Cell type: K-562, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
88% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 40%,
"5_TxWk": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: TRP47, BCL6, FOXA2, MYCN, CHD2, MEIS1, ZFX, XBP1, WT1, ZSCAN5A, ZBTB48, FOXA1, TET2, ERG3, ZNF770, ERG2, ZFHX2, KDM1A, ZNF90, MYC, RUNX2, BRG1, SMARCA4, SP140, ZIC2, TCF4, GRHL3, ARNT, BHLHE22, MAX, ZNF143, FOS, PLAG1, ZNF573, CCAR2, OCA2, EGR2, CTCF, E2F6, HEXIM1, POU2F3, RNF2, BRD4, TCF3, MAZ, AATF, STAG1
- Target gene symbol (double-evidenced CRMs): ABCG1,RSPH1,UMODL1,SLC37A1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000177398,
ENSG00000160179,
ENSG00000160188,
ENSG00000160190,
- Related loop:
chr21:41200000-41225000~~chr21:42475000-42500000,
chr21:41600000-41625000~~chr21:42450000-42475000,
chr21:41650000-41675000~~chr21:42475000-42500000,
chr21:41700000-41725000~~chr21:42475000-42500000,
chr21:41800000-41825000~~chr21:42475000-42500000,
chr21:41900000-41925000~~chr21:42475000-42500000,
chr21:41950000-41975000~~chr21:42475000-42500000,
chr21:42125000-42150000~~chr21:42450000-42475000,
chr21:42125000-42150000~~chr21:42475000-42500000,
chr21:42150000-42175000~~chr21:42450000-42475000,
chr21:42300000-42325000~~chr21:42450000-42475000,
chr21:42450000-42475000~~chr21:42550000-42575000,
chr21:42466723-42468288~~chr21:42517954-42519108,
chr21:42466723-42468288~~chr21:42536785-42538249,
chr21:42466738-42468349~~chr21:42512702-42515312,
chr21:42466738-42468349~~chr21:42536098-42538505,
chr21:42466750-42468364~~chr21:42534380-42538530,
chr21:42466752-42469410~~chr21:42536796-42538220,
chr21:42466778-42468284~~chr21:42536154-42538496,
chr21:42466880-42468218~~chr21:42535463-42538505,
chr21:42473977-42475276~~chr21:42512630-42515252,
chr21:42475000-42500000~~chr21:42575000-42600000,
chr21:42475000-42500000~~chr21:43250000-43275000,
chr21:42475000-42500000~~chr21:43300000-43325000,