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Basic information

CohesinDB ID: CDBP00420370

Locus: chr21-42488988-42489705

Data sourse: GSE67783, GSE86191, GSE98367, GSE120943, ENCSR153HNT

Cell type: HCT-116, Monocytes, K-562, HSPC, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: SA1,Rad21,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 88% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "14_ReprPCWk": 44%, "15_Quies": 38%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: BCL6, ZNF707, ZNF621, ZFX, MTA2, STAT1, NONO, ZNF473, ZBTB33, SUZ12, DDX5, ZNF662, ZKSCAN1, HDGF, EHMT2, BRD9, ZNF148, NFIB, ZNF444, ZNF311, HMBOX1, STAT3, ZNF449, ZNF544, STAG1, NCOA1, CTCF, TCF12, MAFK, HSF1, ZNF776, MAZ, BRCA1, MLLT1

Target gene symbol (double-evidenced CRMs): BACE2,SLC37A1,C2CD2,RSPH1,PRDM15,UMODL1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 6

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000182240, ENSG00000141956, ENSG00000157617, ENSG00000177398, ENSG00000160188, ENSG00000160190,

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Deatailed information for cohesin site CDBP00420370