- Basic information
- CohesinDB ID: CDBP00420377
- Locus: chr21-42508152-42508427
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Data sourse: GSE67783, ENCSR153HNT, GSE86191
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Cell type: K-562, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
86% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 64%,
"14_ReprPCWk": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RELA, CDX2, ZNF384, CEBPB, FOXA2, TEAD1, SCRT2, TOP2A, ZFX, PBX4, ESR1, SCRT1, ZSCAN16, NKX2-1, GATA3, FOXA1, TEAD4, ZNF175, RBPJ, HNF4A
- Target gene symbol (double-evidenced CRMs): PRDM15,SLC37A1,UBASH3A,ABCG1,TMPRSS3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 2
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000141956,
ENSG00000160179,
ENSG00000160183,
ENSG00000160185,
ENSG00000160190,
- Related loop:
chr21:41800000-41825000~~chr21:42500000-42525000,
chr21:42300000-42325000~~chr21:42500000-42525000,
chr21:42400000-42425000~~chr21:42500000-42525000,
chr21:42466738-42468349~~chr21:42512702-42515312,
chr21:42473977-42475276~~chr21:42512630-42515252,