- Basic information
- CohesinDB ID: CDBP00420412
- Locus: chr21-42599440-42600439
-
Data sourse: GSE67783, GSE86191, ENCSR153HNT, GSE83726, GSE68388
-
Cell type: RH4, HCT-116, K-562, HSPC, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SMC1
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
86% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 50%,
"14_ReprPCWk": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: ZNF394, RUNX1, FOSL1, POU2F2, CHD8, BRD1, PGR, MYCN, CREM, RBPJ, EBF1, ZFX, ZNF263, ZBTB48, WT1, DUX4, FOXA1, TET2, SUZ12, ERG, YY1, RELA, TARDBP, JUNB, NFKB2, MYC, BRG1, RUNX3, SP140, GRHL3, SKIL, HIF1A, ARNT, TFDP1, SMC3, BATF, ETV6, PAX5, TP63, FOS, IKZF1, NRIP1, MAX, MED1, ZNF141, TRIM28, CREB1, NR2F1, SNAI2, EZH2, ESR1, ZNF334, SETDB1, NFKB1, CTCF, TCF12, SP1, BHLHE40, AR, IRF4, GATAD2B, HEXIM1, IKZF2, BRD4, RELB, MAZ, ZIM3, ZNF555, STAG1, AHR, EED
- Target gene symbol (double-evidenced CRMs): RRP1B,HSF2BP,CBS,ABCG1,PKNOX1,WDR4,UMODL1,PDE9A,SLC37A1,RSPH1,U2AF1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000177398,
ENSG00000160179,
ENSG00000160188,
ENSG00000160190,
ENSG00000160191,
ENSG00000160193,
ENSG00000160199,
ENSG00000160200,
ENSG00000160201,
ENSG00000160207,
ENSG00000160208,
- Related loop:
chr21:42125000-42150000~~chr21:42575000-42600000,
chr21:42150000-42175000~~chr21:42575000-42600000,
chr21:42300000-42325000~~chr21:42575000-42600000,
chr21:42475000-42500000~~chr21:42575000-42600000,
chr21:42575000-42600000~~chr21:42675000-42700000,
chr21:42575000-42600000~~chr21:42700000-42725000,
chr21:42575000-42600000~~chr21:42725000-42750000,
chr21:42575000-42600000~~chr21:42750000-42775000,
chr21:42575000-42600000~~chr21:42775000-42800000,
chr21:42575000-42600000~~chr21:42800000-42825000,
chr21:42575000-42600000~~chr21:42825000-42850000,
chr21:42575000-42600000~~chr21:42850000-42875000,
chr21:42575000-42600000~~chr21:42950000-42975000,
chr21:42575000-42600000~~chr21:43000000-43025000,
chr21:42575000-42600000~~chr21:43100000-43125000,
chr21:42575000-42600000~~chr21:43175000-43200000,
chr21:42575000-42600000~~chr21:43300000-43325000,
chr21:42575000-42600000~~chr21:43575000-43600000,
chr21:42575000-42600000~~chr21:43600000-43625000,
chr21:42575000-42600000~~chr21:43625000-43650000,
chr21:42591800-42594557~~chr21:42817599-42819253,
chr21:42591816-42594710~~chr21:42817609-42819795,
chr21:42591930-42594651~~chr21:42817479-42819462,
chr21:42592083-42595449~~chr21:42817516-42819501,
chr21:42592083-42595449~~chr21:42832828-42834282,
chr21:42592083-42595449~~chr21:42863770-42864944,
chr21:42592094-42594696~~chr21:42816981-42819855,
chr21:42592095-42594654~~chr21:42817473-42819754,
chr21:42592115-42595504~~chr21:42832880-42834268,
chr21:42592185-42594697~~chr21:42817666-42819271,
chr21:42592203-42594584~~chr21:42817512-42819474,
chr21:42592223-42594608~~chr21:42817647-42819424,
chr21:42592228-42594698~~chr21:42817557-42819404,
chr21:42592229-42594657~~chr21:42817512-42819518,
chr21:42592229-42594657~~chr21:42832535-42834269,
chr21:42592232-42594552~~chr21:42816994-42819826,
chr21:42592233-42594706~~chr21:42817623-42819579,
chr21:42592240-42594527~~chr21:42817801-42819538,
chr21:42592240-42594527~~chr21:42832592-42834225,
chr21:42592259-42595490~~chr21:42817071-42819521,
chr21:42592259-42595490~~chr21:42830397-42831857,
chr21:42592259-42595490~~chr21:42832814-42834600,
chr21:42592286-42594690~~chr21:42817550-42819555,
chr21:42592287-42594650~~chr21:42817467-42819560,
chr21:42592306-42594651~~chr21:42817594-42819293,
chr21:42592309-42594705~~chr21:42817625-42819509,
chr21:42592330-42594539~~chr21:42861258-42862634,
chr21:42592336-42594720~~chr21:42817462-42819526,
chr21:42592439-42594535~~chr21:42817761-42819521,
chr21:42592470-42594527~~chr21:42817758-42819553,
chr21:42592470-42594527~~chr21:42832538-42834234,
chr21:42592470-42595465~~chr21:42817608-42819476,
chr21:42592472-42595486~~chr21:42817007-42819565,
chr21:42592472-42595486~~chr21:42832806-42834627,
chr21:42592503-42594551~~chr21:42817739-42819439,
chr21:42592534-42594617~~chr21:42817712-42819599,
chr21:42592557-42594649~~chr21:42817499-42819241,
chr21:42592645-42594660~~chr21:42817615-42819165,
chr21:42592654-42594700~~chr21:42817528-42819098,
chr21:42592654-42594700~~chr21:42830471-42831810,
chr21:42600000-42625000~~chr21:42700000-42725000,
chr21:42600000-42625000~~chr21:42725000-42750000,
chr21:42600000-42625000~~chr21:42800000-42825000,
chr21:42600000-42625000~~chr21:43025000-43050000,
chr21:42600000-42625000~~chr21:43175000-43200000,
chr21:42600000-42625000~~chr21:43625000-43650000,
chr21:42600000-42625000~~chr21:43650000-43675000,
chr21:6425000-6450000~~chr21:42575000-42600000,