- Basic information
- CohesinDB ID: CDBP00420415
- Locus: chr21-42609794-42610085
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Data sourse: GSE93080, GSE86191
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Cell type: GM12878, HCT-116
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: NIPBL,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
86% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 47%,
"14_ReprPCWk": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFIA, XBP1, PBX2, MLL4, ATF3, NFIC, ZNF362, RUNX3, CBFB, DPF1, PAX5, MAF, JMJD1C, TRIM28, ZNF26, ESR1, USF2, CTCF, MNT, DPF2, IRF4, RAD51, ZNF677, EHMT2, EED, POU2F2, CHD8, MYCN, TOP2A, DDX5, SP4, PBX1, OGG1, MYC, TRIP13, ONECUT1, ZNF2, STAT3, IKZF1, NFE2, NR3C1, ESRRA, KMT2A, EZH2, ZHX2, SPI1, INTS13, ZNF182, HCFC1, RELB, NFYB, RUNX1, BCL6, CRY1, AFF4, ZFX, CBX8, TRIM22, PRDM10, NFYC, RUNX2, ARNT, NFIB, PRDM9, NFYA, ETV6, PBX3, SP2, FOS, CDK8, SETDB1, USF1, NIPBL, SP1, BCL11A, REST, RBM25, ATF7, TCF3, SMC3, MLLT1, CBFA2T2, CREM, EBF1, ZSCAN16, WT1, MEF2C, TCF7, YY1, RELA, ICE1, BATF, MAX, ZNF143, GATA1, PLAG1, KLF4, NR2F1, TP53, PKNOX1, NFKB1, PHOX2B, ZFP28, BHLHE40, AR, PAX3-FOXO1, RXR, IKZF2, BRD4, ZFP42
- Target gene symbol (double-evidenced CRMs): RRP1B,PKNOX1,PDE9A,HSF2BP,CBS
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000160191,
ENSG00000160199,
ENSG00000160200,
ENSG00000160207,
ENSG00000160208,
- Related loop:
chr21:42600000-42625000~~chr21:42700000-42725000,
chr21:42600000-42625000~~chr21:42725000-42750000,
chr21:42600000-42625000~~chr21:42800000-42825000,
chr21:42600000-42625000~~chr21:43025000-43050000,
chr21:42600000-42625000~~chr21:43175000-43200000,
chr21:42600000-42625000~~chr21:43625000-43650000,
chr21:42600000-42625000~~chr21:43650000-43675000,