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Basic information

CohesinDB ID: CDBP00420430

Locus: chr21-42646879-42647225

Data sourse: GSE129526, ENCSR153HNT, GSE86191

Cell type: K-562, HCT-116

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 86% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 47%, "14_ReprPCWk": 43%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, XBP1, PATZ1, FOXA1, SUZ12, PBX2, ZFHX2, ATF3, ZFP64, CHD7, PRDM1, ATF4, CBFB, ZNF189, DPF1, MITF, ZNF629, ZNF506, TEAD1, TRIM28, ZNF121, ETV1, ESR1, HDAC8, USF2, CTCF, JUN, EP300, MNT, SOX5, E2F6, TRIM24, RAD51, ZNF528, TEAD4, FOXA3, ZNF175, TFAP2C, GLIS1, CHD8, BRD1, ZSCAN5D, ZNF263, POU5F1, TOP2A, MYCN, KDM4C, CTBP1, ZSCAN21, ZBTB17, ZBTB48, SAP130, ERG, ZBTB21, ASCL1, OGG1, MYC, SMARCA4, HOMEZ, RAD21, GRHL3, RXRA, FOXK2, STAT3, XRCC5, PRDM14, IKZF1, DNMT3B, CEBPB, ESRRA, HNRNPL, CREB1, EZH2, GRHL2, SPI1, PCBP1, GATA2, FLI1, DRAP1, NR2C2, MRTFB, ATF1, ETV5, RUNX1, BCL6, CEBPA, HDAC1, CRY1, ZNF335, ZFX, SMAD3, TET2, ERG3, ZNF770, SMARCC1, PRDM10, MEF2A, PBX4, ATF2, ZNF48, SMAD4, CBFA2T3, FOS, TEAD3, SCRT2, ZNF3, L3MBTL2, MAFK, BCL11A, USF1, REST, ZNF479, ATF7, HNRNPLL, FOXP1, AATF, SMC3, STAG1, ZNF394, TRP47, CBFA2T2, ZNF283, FOXA2, CBX3, MTA3, SS18, ZNF600, ZNF692, WT1, ESR2, MEF2C, CDK9, BCL3, ZKSCAN1, ZNF589, YY1, RELA, NEUROD1, JUNB, BRG1, SP140, ZFP36, ZIC2, HIF1A, OTX2, MGA, TAL1, MAX, NRIP1, ZNF143, GATA1, CBX2, PLAG1, CEBPG, GFI1B, NR2F2, NR2F1, KDM5B, PKNOX1, ZBTB6, ZSCAN22, EGR2, BRD2, ARID4B, BHLHE40, AR, RXR, ZNF366, TFIIIC, ZBTB26, RNF2, HSF1, JUND, BRD4, SCRT1, CLOCK, MAZ, MEF2D, ZFP42, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): PKNOX1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000160199,

eachgene

Deatailed information for cohesin site CDBP00420430