- Basic information
- CohesinDB ID: CDBP00420451
- Locus: chr21-42707172-42707738
-
Data sourse: GSE206145-GSE177045, GSE67783, GSE86191, ENCSR153HNT, GSE97394
-
Cell type: MCF-7, HCT-116, K-562, HSPC, HUES64
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: Mau2,SA1,Rad21
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
86% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 36%,
"5_TxWk": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: NCOA2, GLIS1, RUNX1, CBFA2T2, CHD8, NANOG, FOXA2, MYCN, CREM, ZNF263, PAF1, ZFX, POU5F1, XBP1, ZNF207, ZBTB48, WT1, SMAD3, SOX2, TEAD4, ZNF317, CBX8, DDX5, PBX2, RELA, ATF3, MYC, RAD21, SP140, GRHL3, HIF1A, CHD7, ATF2, STAT3, MAX, MAF1, ZNF143, MITF, PLAG1, GMEB1, CBX2, TEAD3, ZEB1, NCOA3, CREB1, TFAP2C, EZH2, OCA2, USF2, NFKB1, CTCF, RBM22, USF1, EP300, SP1, BHLHE40, AR, EGR1, HSF1, RAD51, NCOR1, CTBP2, BCOR, E2F1, MAZ, SMC3, ATF1, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): SLC37A1,PDE9A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 39
- Number of somatic mutations (non-coding): 0
- Related genes and loops