- Basic information
- CohesinDB ID: CDBP00420466
- Locus: chr21-42749851-42750087
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Data sourse: GSE206145-GSE177045, GSE67783, ENCSR153HNT
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Cell type: K-562, MCF-7, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Mau2,SA1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
85% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 49%,
"15_Quies": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, NME2, FOXA1, SUZ12, ZFHX2, LYL1, ATF3, BMI1, CBFB, MECOM, ZNF736, JMJD1C, MAF, TEAD1, ELF1, TRIM28, RBM39, LMO2, ESR1, OCA2, MLL, USF2, CTCF, JUN, BAF155, MNT, GATA6, E2F6, TRIM24, ZNF528, TEAD4, KMT2B, FOXA3, TFAP2C, EED, GLIS1, POU2F2, CHD8, BRD1, MYCN, ZNF263, RUNX1T1, ZBTB48, STAT1, ZNF563, ERG2, ERG, PBX1, OGG1, MYC, SMARCA4, RAD21, GRHL3, GABPA, STAT3, NKX3-1, IKZF1, NFE2, DNMT3B, ZNF667, NR3C1, CEBPB, KMT2A, EZH2, GRHL2, GABPB1, SPI1, PCBP1, GATA2, INTS13, MXD3, FLI1, HCFC1R1, RUNX1, BCL6, SMC1A, CEBPA, SIRT6, ZFX, TET2, CBX8, ERG3, ZNF18, PRDM10, RARA, CREBBP, PRPF4, TAF15, ARNT, ZNF48, CHD1, FOS, CDK8, TEAD3, ZEB1, KDM6B, MYB, ZNF3, L3MBTL2, EVI1, USF1, BCL11A, SP1, REST, ASH2L, HNRNPLL, TCF3, FOXP1, AATF, SMC3, STAG1, NFATC3, SKI, TRP47, CBFA2T2, MEF2B, FOXA2, AGO1, SS18, WT1, MEF2C, CDK9, HOXB13, YY1, RELA, SP140, ZFP36, HIF1A, TAL1, MAX, ZNF143, AGO2, HAND2, CBX2, PLAG1, KLF4, NR2F2, NR2F1, KDM5B, MED, ZNF334, EGR2, TBX21, AR, RXR, HSF1, RNF2, BRD4, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): C2CD2,HSF2BP,ABCG1,SLC37A1,PDE9A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 13
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000157617,
ENSG00000160179,
ENSG00000160190,
ENSG00000160191,
ENSG00000160207,
- Related loop:
chr21:27500000-27525000~~chr21:42750000-42775000,
chr21:41900000-41925000~~chr21:42750000-42775000,
chr21:42275000-42300000~~chr21:42750000-42775000,
chr21:42300000-42325000~~chr21:42750000-42775000,
chr21:42575000-42600000~~chr21:42725000-42750000,
chr21:42575000-42600000~~chr21:42750000-42775000,
chr21:42600000-42625000~~chr21:42725000-42750000,
chr21:42725000-42750000~~chr21:43175000-43200000,
chr21:42725000-42750000~~chr21:43200000-43225000,
chr21:42725000-42750000~~chr21:43575000-43600000,
chr21:42750000-42775000~~chr21:43175000-43200000,
chr21:6425000-6450000~~chr21:42725000-42750000,