- Basic information
- CohesinDB ID: CDBP00420476
- Locus: chr21-42773602-42774406
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Data sourse: GSE67783, ENCSR153HNT, GSE86191
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Cell type: K-562, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
83% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 46%,
"4_Tx": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CBX2, MYC, THAP1, PAF1, SCRT1, CTCF, TP63, HOXB13, KLF1
- Target gene symbol (double-evidenced CRMs): C2CD2,SLC37A1,PDE9A,ABCG1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 104
- Number of somatic mutations (non-coding): 8
- Related genes and loops
- Related gene:
ENSG00000157617,
ENSG00000160179,
ENSG00000160190,
ENSG00000160191,
- Related loop:
chr21:27500000-27525000~~chr21:42750000-42775000,
chr21:41700000-41725000~~chr21:42775000-42800000,
chr21:41900000-41925000~~chr21:42750000-42775000,
chr21:42025000-42050000~~chr21:42775000-42800000,
chr21:42125000-42150000~~chr21:42775000-42800000,
chr21:42275000-42300000~~chr21:42750000-42775000,
chr21:42275000-42300000~~chr21:42775000-42800000,
chr21:42300000-42325000~~chr21:42750000-42775000,
chr21:42300000-42325000~~chr21:42775000-42800000,
chr21:42575000-42600000~~chr21:42750000-42775000,
chr21:42575000-42600000~~chr21:42775000-42800000,
chr21:42675000-42700000~~chr21:42775000-42800000,
chr21:42750000-42775000~~chr21:43175000-43200000,
chr21:42775000-42800000~~chr21:43175000-43200000,
chr21:42775000-42800000~~chr21:43200000-43225000,