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Basic information

CohesinDB ID: CDBP00420479

Locus: chr21-42779308-42780010

Data sourse: GSE67783, GSE111913, ENCSR153HNT, GSE86191

Cell type: K-562, RT-112, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21,SA2,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 83% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "13_ReprPC": 27%, "14_ReprPCWk": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, NFIA, ZNF426, NME2, FOXA1, RXRB, MLL4, KDM3A, HDGF, THAP1, IKZF3, MORC2, PAX5, TEAD1, ZNF121, LMO2, OCA2, PITX3, ZNF561, ZNF577, E4F1, ARID5B, SOX5, E2F4, ZNF528, KMT2B, ZNF555, GATAD2A, JARID2, ZNF263, POU5F1, TOP2A, CTBP1, ZNF433, STAT1, SAP130, ERG, ZBTB8A, EZH1, SMARCA4, ZNF398, RCOR1, NR2F6, CEBPB, HNRNPL, CREB1, BMPR1A, GABPB1, ZHX2, MIXL1, KLF17, ZNF257, GATA2, ZNF644, MXD3, FLI1, DRAP1, MXI1, RUNX1, CEBPA, NKX2-2, TET2, SP5, SMARCC1, PRDM10, ZBTB2, ATF2, EVI1, IKZF5, RBM25, ETV4, NFATC3, CBFA2T2, CBX3, CHD2, SS18, PAF1, NFATC1, WT1, NEUROD1, ZNF510, ZNF311, SPIB, PLAG1, KLF4, BCL11B, BCL6B, EGR2, ELF3, ARID4B, RXR, EGLN2, ZNF366, HSF1, ZBTB26, NCOR1, FOSL1, XBP1, KDM4B, ZNF101, HNRNPK, ATF3, ZFP64, CBFB, TP63, MITF, ZNF467, MAF, JMJD1C, ELF1, RBM39, SNAI2, CTCF, JUN, MNT, ZBTB20, LMO1, RYBP, SIX5, ZNF423, PDX1, TFAP2C, RBPJ, MLX, ZSCAN21, ZBTB17, ZBTB48, ZNF317, SRF, DDX5, KDM4A, HOMEZ, FOXP2, PRDM14, MIER3, NR3C1, STAT5B, KMT2A, ZBTB11, KLF8, GRHL2, ZNF292, EBF3, NFIL3, THAP11, EZH2phosphoT487, SOX13, ZNF770, SP3, ARNT, ZNF48, ZNF10, HMGXB4, TEAD3, ZXDB, U2AF1, KLF9, SP1, TFAP2A, BCL11A, ATF7, ASH2L, CTBP2, GLIS2, ZNF623, SMC3, STAG1, STAG2, ZNF394, TRP47, AGO1, ZNF580, KDM1A, BRG1, ZIC2, PCGF1, GATA3, TAL1, NRIP1, ZNF143, AGO2, MTA1, CBX2, TP53, ZNF334, ZNF140, BRD2, KAT8, TBX21, EGR1, RNF2, BRD4, JUND, PGR, ZNF697, PATZ1, RING1B, UBTF, CHD7, ZNF444, MXD4, ZNF189, KLF6, SAP30, ESR1, KLF1, E2F6, RFX5, GTF2F1, GLIS1, POU2F2, ZNF778, ZSCAN5A, ERG2, SP4, OGG1, ETS1, MYC, GABPA, STAT3, IKZF1, DNMT3B, SRSF3, EZH2, PHF8, SPI1, PCBP1, HDAC2, GATAD2B, ZNF490, ETV5, BCL6, SIN3A, ERG3, RARA, CREBBP, NFYC, TAF15, ZNF781, SMAD4, ZNF518A, CDK8, ZEB1, ZMYM3, HNF4A, REST, ARID1A, HNRNPLL, BCOR, FOXP1, AATF, ZNF34, ZNF692, GTF2B, ZNF574, ZNF823, RELA, TARDBP, MAX, GFI1B, NR2F1, KDM5B, PKNOX1, MYOD1, AR, ZBTB16, RBAK, ZNF324, HEXIM1, DMAP1, AHR, MBD3, HMG20A, SUZ12, RBFOX2, ZNF28, ZFHX2, ZNF90, PRDM1, PRDM12, MECOM, ZNF736, ZNF629, KLF5, TRIM28, TCF12, EP300, BAF155, GATA6, ZNF512B, E2F1, SMC1, FOXA3, ZNF175, EED, CHD8, BRD1, MYCN, CDK7, RUNX1T1, GATAD1, ASCL1, ZNF341, RAD21, GRHL3, ZNF614, XRCC5, NFE2, ZNF639, ZNF750, TFE3, ZNF664, ZGPAT, PTBP1, CBX1, SMC1A, SIRT6, ZNF335, ZFX, ZNF534, PCBP2, CBX8, TWIST1, NOTCH1, RUNX2, OSR2, FOS, CHD1, SUPT5H, MED1, KDM6B, MYB, SCRT2, CEBPD, ZNF558, SETDB1, ZBTB7A, PHIP, TCF3, SKI, ZNF283, FOXA2, RBBP5, ZNF600, CDK9, HOXB13, YY1, SP140, HIF1A, OTX2, ZNF449, GATA1, HAND2, CEBPG, SP7, NCOA3, NR2F2, ZNF687, ZNF213, NFKBIZ, BHLHE40, TAF1, ZNF579, ZBTB40, ZBTB42, MAZ, ZNF24

Target gene symbol (double-evidenced CRMs): SLC37A1,ABCG1,PDE9A,UMODL1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000177398, ENSG00000160179, ENSG00000160190, ENSG00000160191,

eachgene

Deatailed information for cohesin site CDBP00420479