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Basic information

CohesinDB ID: CDBP00420487

Locus: chr21-42799515-42801184

Data sourse: ENCSR000BLD, GSE67783, GSE86191, ENCSR000BSB, ENCSR153HNT, GSE68388, GSE131606, GSE50893, GSE126755, GSE97394

Cell type: GM12892, H1-hESC, HCT-116, SNYDER, GM2610, GM12878, GM12891, HUES64, K-562, Neutrophil, HSPC, HuCC-T1, DKO

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 4% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.856

Subunit: SA1,Rad21,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 83% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 42%, "14_ReprPCWk": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, FOSL1, POU2F2, MEF2B, PPARG, CHD8, MTA3, CREM, EBF1, BCL6, ZFX, ZNF600, MTA2, SMAD3, ZBTB48, WT1, FOXA1, SRF, ERG3, CBX8, NBN, ERG2, ZFHX2, ERG, HOXC5, CREBBP, ZNF384, JUNB, ATF3, NFIC, MYC, SMARCA4, ZNF184, RUNX3, PRDM1, PBX4, HOMEZ, RAD21, NKX2-1, ATF2, BATF3, BATF, GABPA, PAX5, PBX3, SPIB, ZNF143, IKZF1, RCOR1, FOS, ZNF639, MAX, CBX2, ZNF629, SP7, ZEB1, BCLAF1, KMT2A, CREB1, SNAI2, TRIM28, NR1H2, EGR2, JUN, ELF3, TCF12, BCL11A, KLF1, TBX21, SPI1, CTCF, KLF17, CBFA2T2, DPF2, IRF4, ATF7, RNF2, IKZF2, BRD4, JUND, TCF3, BCOR, ZNF490, EED

Target gene symbol (double-evidenced CRMs): ABCG1,TMPRSS3,PRDM15,BACE2,UBASH3A,TFF2,SLC37A1,HSF2BP,PDE9A,FAM3B,UMODL1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 4

Related genes and loops

Related gene: ENSG00000182240, ENSG00000183844, ENSG00000141956, ENSG00000177398, ENSG00000160179, ENSG00000160181, ENSG00000160183, ENSG00000160185, ENSG00000160190, ENSG00000160191, ENSG00000160207,

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Deatailed information for cohesin site CDBP00420487