- Basic information
- CohesinDB ID: CDBP00420488
- Locus: chr21-42801570-42802027
-
Data sourse: GSE25021, GSE72082, GSE206145-GSE177045
-
Cell type: MCF-7
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: Mau2,SA1,Rad21
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
83% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 50%,
"14_ReprPCWk": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: NANOG, FOXA2, WT1, FOXA1, HOXB13, ERG, CREBBP, RUNX2, GATA4, OSR2, GATA3, NKX3-1, ZNF467, CREB1, PIAS1, ESR1, BAF155, AR, GATA2, BRD4, FOXP1
- Target gene symbol (double-evidenced CRMs): SLC37A1,FAM3B,ABCG1,BACE2,UMODL1,PDE9A,TFF2,TMPRSS3,HSF2BP,PRDM15,UBASH3A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
ENSG00000182240,
ENSG00000183844,
ENSG00000141956,
ENSG00000177398,
ENSG00000160179,
ENSG00000160181,
ENSG00000160183,
ENSG00000160185,
ENSG00000160190,
ENSG00000160191,
ENSG00000160207,
- Related loop:
chr21:41275000-41300000~~chr21:42800000-42825000,
chr21:41575000-41600000~~chr21:42800000-42825000,
chr21:41700000-41725000~~chr21:42775000-42800000,
chr21:41800000-41825000~~chr21:42800000-42825000,
chr21:42025000-42050000~~chr21:42775000-42800000,
chr21:42125000-42150000~~chr21:42775000-42800000,
chr21:42125000-42150000~~chr21:42800000-42825000,
chr21:42150000-42175000~~chr21:42800000-42825000,
chr21:42175000-42200000~~chr21:42800000-42825000,
chr21:42200000-42225000~~chr21:42800000-42825000,
chr21:42275000-42300000~~chr21:42775000-42800000,
chr21:42300000-42325000~~chr21:42775000-42800000,
chr21:42300000-42325000~~chr21:42800000-42825000,
chr21:42325000-42350000~~chr21:42800000-42825000,
chr21:42375000-42400000~~chr21:42800000-42825000,
chr21:42400000-42425000~~chr21:42800000-42825000,
chr21:42525000-42550000~~chr21:42800000-42825000,
chr21:42550000-42575000~~chr21:42800000-42825000,
chr21:42575000-42600000~~chr21:42775000-42800000,
chr21:42575000-42600000~~chr21:42800000-42825000,
chr21:42600000-42625000~~chr21:42800000-42825000,
chr21:42625000-42650000~~chr21:42800000-42825000,
chr21:42650000-42675000~~chr21:42800000-42825000,
chr21:42675000-42700000~~chr21:42775000-42800000,
chr21:42675000-42700000~~chr21:42800000-42825000,
chr21:42700000-42725000~~chr21:42800000-42825000,
chr21:42775000-42800000~~chr21:43175000-43200000,
chr21:42775000-42800000~~chr21:43200000-43225000,
chr21:42800000-42825000~~chr21:43175000-43200000,
chr21:42800000-42825000~~chr21:43300000-43325000,
chr21:42800000-42825000~~chr21:43575000-43600000,
chr21:42800000-42825000~~chr21:43625000-43650000,
chr21:42806064-42807428~~chr21:43644880-43647795,