- Basic information
- CohesinDB ID: CDBP00420490
- Locus: chr21-42806323-42807117
-
Data sourse: GSE105028, GSE97394, GSE111913, GSE64758
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Cell type: RT-112, H1-hESC, HUES64, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: NIPBL,Rad21,SA2,SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
83% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 37%,
"14_ReprPCWk": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: HMG20A, SOX2, FOXA1, RXRB, ZFP64, THAP1, CHD7, JMJD1C, TEAD1, TRIM28, LMO2, ESR1, RCOR2, CTCF, TCF12, EP300, GATA6, SOX5, E2F6, ZNF528, TEAD4, ZNF175, GATAD2A, RBPJ, EED, MLX, JARID2, NANOG, CHD8, POU5F1, MYCN, RUNX1T1, ZBTB48, SAP130, ERG, EOMES, RAD21, GABPA, NFE2, NR2F6, CREB1, SPI1, MIXL1, TFE3, HDAC2, GATA2, FLI1, RUNX1, THAP11, CTNNB1, SMC1A, BCL6, CEBPA, SOX13, ZFX, SMAD3, TET2, CREBBP, SMAD2, CDK6, SMAD4, HMGXB4, TEAD3, BCL11A, IKZF5, ARID1A, BCOR, TCF3, SMC3, ZNF207, FOXA2, WT1, HOXB13, YY1, RELA, NEUROD1, SP140, HIF1A, OTX2, MAX, CBX2, CEBPG, NCOA3, ZNF334, ELF3, T, KAT8, NFKBIZ, AR, ARID4B, ZBTB26, ZFP42, DMAP1
- Target gene symbol (double-evidenced CRMs): PRDM15,UBASH3A,TMPRSS3,TFF2,UMODL1,BACE2,FAM3B,HSF2BP,ABCG1,PDE9A,SLC37A1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000182240,
ENSG00000183844,
ENSG00000141956,
ENSG00000177398,
ENSG00000160179,
ENSG00000160181,
ENSG00000160183,
ENSG00000160185,
ENSG00000160190,
ENSG00000160191,
ENSG00000160207,
- Related loop:
chr21:41275000-41300000~~chr21:42800000-42825000,
chr21:41575000-41600000~~chr21:42800000-42825000,
chr21:41800000-41825000~~chr21:42800000-42825000,
chr21:42125000-42150000~~chr21:42800000-42825000,
chr21:42150000-42175000~~chr21:42800000-42825000,
chr21:42175000-42200000~~chr21:42800000-42825000,
chr21:42200000-42225000~~chr21:42800000-42825000,
chr21:42300000-42325000~~chr21:42800000-42825000,
chr21:42325000-42350000~~chr21:42800000-42825000,
chr21:42375000-42400000~~chr21:42800000-42825000,
chr21:42400000-42425000~~chr21:42800000-42825000,
chr21:42525000-42550000~~chr21:42800000-42825000,
chr21:42550000-42575000~~chr21:42800000-42825000,
chr21:42575000-42600000~~chr21:42800000-42825000,
chr21:42600000-42625000~~chr21:42800000-42825000,
chr21:42625000-42650000~~chr21:42800000-42825000,
chr21:42650000-42675000~~chr21:42800000-42825000,
chr21:42675000-42700000~~chr21:42800000-42825000,
chr21:42700000-42725000~~chr21:42800000-42825000,
chr21:42800000-42825000~~chr21:43175000-43200000,
chr21:42800000-42825000~~chr21:43300000-43325000,
chr21:42800000-42825000~~chr21:43575000-43600000,
chr21:42800000-42825000~~chr21:43625000-43650000,
chr21:42806064-42807428~~chr21:43644880-43647795,