- Basic information
- CohesinDB ID: CDBP00420495
- Locus: chr21-42812479-42812787
-
Data sourse: GSE101921, GSE126755, GSE85526, GSE68388
-
Cell type: HMEC, HuCC-T1, Neutrophil, HEKn
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Rad21,SA2,SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
83% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 50%,
"14_ReprPCWk": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: PGR, TP53, BRD4, ESR1, TP63, EHF
- Target gene symbol (double-evidenced CRMs): PRDM15,TFF2,UMODL1,FAM3B,PDE9A,UBASH3A,TMPRSS3,HSF2BP,ABCG1,BACE2,SLC37A1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000182240,
ENSG00000183844,
ENSG00000141956,
ENSG00000177398,
ENSG00000160179,
ENSG00000160181,
ENSG00000160183,
ENSG00000160185,
ENSG00000160190,
ENSG00000160191,
ENSG00000160207,
- Related loop:
chr21:41275000-41300000~~chr21:42800000-42825000,
chr21:41575000-41600000~~chr21:42800000-42825000,
chr21:41800000-41825000~~chr21:42800000-42825000,
chr21:42125000-42150000~~chr21:42800000-42825000,
chr21:42144207-42146848~~chr21:42816981-42819855,
chr21:42144672-42146558~~chr21:42817722-42819834,
chr21:42144776-42146791~~chr21:42817609-42819795,
chr21:42150000-42175000~~chr21:42800000-42825000,
chr21:42175000-42200000~~chr21:42800000-42825000,
chr21:42200000-42225000~~chr21:42800000-42825000,
chr21:42300000-42325000~~chr21:42800000-42825000,
chr21:42325000-42350000~~chr21:42800000-42825000,
chr21:42375000-42400000~~chr21:42800000-42825000,
chr21:42400000-42425000~~chr21:42800000-42825000,
chr21:42525000-42550000~~chr21:42800000-42825000,
chr21:42539061-42541105~~chr21:42817512-42819474,
chr21:42539601-42540779~~chr21:42817608-42819476,
chr21:42550000-42575000~~chr21:42800000-42825000,
chr21:42575000-42600000~~chr21:42800000-42825000,
chr21:42591800-42594557~~chr21:42817599-42819253,
chr21:42591816-42594710~~chr21:42817609-42819795,
chr21:42591930-42594651~~chr21:42817479-42819462,
chr21:42592083-42595449~~chr21:42817516-42819501,
chr21:42592094-42594696~~chr21:42816981-42819855,
chr21:42592095-42594654~~chr21:42817473-42819754,
chr21:42592101-42594282~~chr21:42817616-42819574,
chr21:42592185-42594697~~chr21:42817666-42819271,
chr21:42592203-42594584~~chr21:42817512-42819474,
chr21:42592223-42594608~~chr21:42817647-42819424,
chr21:42592228-42594698~~chr21:42817557-42819404,
chr21:42592229-42594657~~chr21:42817512-42819518,
chr21:42592232-42594552~~chr21:42816994-42819826,
chr21:42592233-42594706~~chr21:42817623-42819579,
chr21:42592259-42595490~~chr21:42817071-42819521,
chr21:42592286-42594690~~chr21:42817550-42819555,
chr21:42592287-42594650~~chr21:42817467-42819560,
chr21:42592306-42594651~~chr21:42817594-42819293,
chr21:42592309-42594705~~chr21:42817625-42819509,
chr21:42592336-42594720~~chr21:42817462-42819526,
chr21:42592439-42594535~~chr21:42817761-42819521,
chr21:42592470-42594527~~chr21:42817758-42819553,
chr21:42592470-42595465~~chr21:42817608-42819476,
chr21:42592472-42595486~~chr21:42817007-42819565,
chr21:42592503-42594438~~chr21:42817722-42819834,
chr21:42592503-42594551~~chr21:42817739-42819439,
chr21:42592508-42594238~~chr21:42816981-42819538,
chr21:42592534-42594617~~chr21:42817712-42819599,
chr21:42592557-42594649~~chr21:42817499-42819241,
chr21:42592622-42594193~~chr21:42817638-42819088,
chr21:42592644-42594180~~chr21:42817432-42819171,
chr21:42592645-42594660~~chr21:42817615-42819165,
chr21:42592647-42594289~~chr21:42817691-42819126,
chr21:42592654-42594700~~chr21:42817528-42819098,
chr21:42592693-42594316~~chr21:42817613-42819116,
chr21:42592736-42594162~~chr21:42817665-42819135,
chr21:42592744-42594126~~chr21:42817752-42819044,
chr21:42600000-42625000~~chr21:42800000-42825000,
chr21:42625000-42650000~~chr21:42800000-42825000,
chr21:42650000-42675000~~chr21:42800000-42825000,
chr21:42651607-42653884~~chr21:42817557-42819404,
chr21:42651695-42653675~~chr21:42817609-42819795,
chr21:42651926-42653288~~chr21:42817594-42819293,
chr21:42651964-42653518~~chr21:42817467-42819560,
chr21:42652851-42655141~~chr21:42817499-42819241,
chr21:42675000-42700000~~chr21:42800000-42825000,
chr21:42700000-42725000~~chr21:42800000-42825000,
chr21:42791205-42793251~~chr21:42817675-42819687,
chr21:42791244-42793306~~chr21:42817654-42819493,
chr21:42791318-42793181~~chr21:42817479-42819462,
chr21:42791421-42793239~~chr21:42817550-42819555,
chr21:42800000-42825000~~chr21:43175000-43200000,
chr21:42800000-42825000~~chr21:43300000-43325000,
chr21:42800000-42825000~~chr21:43575000-43600000,
chr21:42800000-42825000~~chr21:43625000-43650000,