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Basic information

CohesinDB ID: CDBP00420513

Locus: chr21-42867885-42870709

Data sourse: GSE206145, GSE67783, ENCSR153HNT, GSE86191

Cell type: K-562, HCT-116, HSPC, RPE

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 83% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "4_Tx": 64%, "5_TxWk": 35%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, NFIA, FOSL1, ZSCAN5C, PATZ1, FOXA1, RBFOX2, LEO1, ZFHX2, HNRNPK, HDGF, ATF3, NFIC, CTCFL, CBFB, MORC2, GLYR1, ZNF189, TP63, CDX2, ELF1, RBM39, SNAI2, SMAD5, ESR1, OCA2, LMO2, USF2, CTCF, JUN, TCF12, KLF1, LMO1, GATA6, SOX4, DEK, ZNF423, GTF2F1, TFAP2C, RBPJ, JARID2, GLIS1, POU2F2, CHD8, BRD1, ZSCAN5D, MYCN, ZNF263, TOP2A, RUNX1T1, ZMYND11, ZBTB17, ZBTB48, ZSCAN5A, STAT1, DDX5, ERG2, SP4, TBP, ERG, PBX1, ASCL1, OGG1, ETS1, MYC, ONECUT1, SMARCA4, ZNF2, RAD21, GRHL3, RXRA, NKX2-1, GABPA, STAT3, APC, XRCC5, PRDM14, IKZF1, DNMT3B, HNRNPH1, NR3C1, CEBPB, SRSF3, HNRNPL, KMT2A, CREB1, KLF8, BMPR1A, EBF3, GABPB1, ZHX2, HDAC2, GATA2, MXD3, FLI1, MXI1, NCOA2, ZNF554, RUNX1, BCL6, SMC1A, CEBPA, SIRT6, CRY1, ZFX, TET2, ERG3, ZNF770, TWIST1, PRDM10, NSD2, CREBBP, ZNF35, ARNT, NFIB, ZNF48, ZNF10, SUPT5H, FOS, CHD1, SMARCB1, ZEB1, MYB, ZNF331, ZNF3, KLF9, SREBF2, ZNF22, RBM22, BCL11A, SP1, HNF4A, IKZF5, ZHX1, ASH2L, TCF3, AATF, SMC3, STAG1, TRP47, CBFA2T2, FOXA2, AGO1, PAF1, ZNF600, WT1, ZBTB33, YY1, RELA, TARDBP, NEUROD1, SP140, TCF4, HIF1A, ZIC2, KLF15, TAL1, MAX, ZNF143, AGO2, PLAG1, CBX2, KLF4, BCL11B, NR2F1, NEUROG2, KDM5B, TP53, EGR2, AR, RXR, EGLN2, HEXIM1, HSF1, ZBTB26, BRD4, MAZ, AHR

Target gene symbol (double-evidenced CRMs): SLC37A1,WDR4,ABCG1,U2AF1,RRP1B,HSF2BP

Function elements

Human SNPs: .

Number of somatic mutations (coding): 14

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000160179, ENSG00000160190, ENSG00000160193, ENSG00000160201, ENSG00000160207, ENSG00000160208,

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Deatailed information for cohesin site CDBP00420513