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Basic information

CohesinDB ID: CDBP00420514

Locus: chr21-42872006-42873778

Data sourse: GSE67783, ENCSR153HNT, GSE86191

Cell type: K-562, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 83% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "4_Tx": 79%, "5_TxWk": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOSL1, BCL6, LDB1, PAF1, ZFX, CTBP1, ZSCAN16, ZMYND11, STAT1, RBFOX2, PBX2, HOXB13, ERG, RELA, RARA, HDGF, NEUROD1, MYC, ZNF184, RXRA, GLYR1, TAL1, CBFA2T3, TP63, NRIP1, SUPT5H, IKZF1, DNMT3B, ESRRA, EZH2, TP53, ESR1, TP73, GABPB1, CTCF, RBM22, SPI1, BCL11A, PAX8, CREB3, RB1, ATF1

Target gene symbol (double-evidenced CRMs): SLC37A1,WDR4,U2AF1,RRP1B,ABCG1,HSF2BP

Function elements

Human SNPs: .

Number of somatic mutations (coding): 84

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000160179, ENSG00000160190, ENSG00000160193, ENSG00000160201, ENSG00000160207, ENSG00000160208,

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Deatailed information for cohesin site CDBP00420514