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Basic information

CohesinDB ID: CDBP00420525

Locus: chr21-42896014-42896815

Data sourse: GSE206145, GSE67783, ENCSR153HNT, GSE86191

Cell type: K-562, HCT-116, HSPC, RPE

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 83% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "5_TxWk": 75%, "4_Tx": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: MYCN, PAF1, NME2, ZFX, ZSCAN16, ZBTB48, ZBTB12, STAT1, FOXA1, DDX5, RBFOX2, HOXB13, HDGF, NEUROD1, MYC, ZNF362, GABPA, ETV6, MAX, GATA1, SUPT5H, AGO2, ZNF639, NR3C1, BCL11B, SUPT16H, CTCF, SPI1, MNT, AR, TRIM24, DDX20, BRD4, FOXP1, ZNF528, MAZ

Target gene symbol (double-evidenced CRMs): UBE2G2,NDUFV3,DNMT3L,CSTB,RRP1B,HSF2BP,RRP1,SUMO3

Function elements

Human SNPs: .

Number of somatic mutations (coding): 2

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000160194, ENSG00000160207, ENSG00000160208, ENSG00000160213, ENSG00000160214, ENSG00000142182, ENSG00000184787, ENSG00000184900,

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Deatailed information for cohesin site CDBP00420525