- Basic information
- CohesinDB ID: CDBP00420526
- Locus: chr21-42897274-42897953
-
Data sourse: GSE206145-GSE177045, GSE67783, ENCSR153HNT, GSE86191
-
Cell type: K-562, MCF-7, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Mau2,SA1,Rad21
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
83% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"4_Tx": 69%,
"5_TxWk": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: MYCN, PAF1, NME2, ZFX, ZSCAN16, ZBTB48, ZBTB12, STAT1, FOXA1, DDX5, RBFOX2, HOXB13, HDGF, NEUROD1, MYC, ZNF362, GABPA, ETV6, MAX, GATA1, SUPT5H, AGO2, ZNF639, NR3C1, BCL11B, SUPT16H, CTCF, SPI1, MNT, AR, TRIM24, DDX20, BRD4, FOXP1, ZNF528, MAZ
- Target gene symbol (double-evidenced CRMs): RRP1,UBE2G2,RRP1B,SUMO3,DNMT3L,NDUFV3,HSF2BP,CSTB
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 4
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000160194,
ENSG00000160207,
ENSG00000160208,
ENSG00000160213,
ENSG00000160214,
ENSG00000142182,
ENSG00000184787,
ENSG00000184900,
- Related loop:
chr21:42875000-42900000~~chr21:43175000-43200000,
chr21:42875000-42900000~~chr21:43325000-43350000,
chr21:42875000-42900000~~chr21:43350000-43375000,
chr21:42875000-42900000~~chr21:43625000-43650000,
chr21:42875000-42900000~~chr21:43650000-43675000,
chr21:42875000-42900000~~chr21:43775000-43800000,
chr21:42875000-42900000~~chr21:44250000-44275000,
chr21:42875000-42900000~~chr21:44800000-44825000,
chr21:42892194-42894528~~chr21:43717961-43720857,
chr21:42900000-42925000~~chr21:43000000-43025000,
chr21:42900000-42925000~~chr21:43025000-43050000,
chr21:42900000-42925000~~chr21:43100000-43125000,
chr21:42900000-42925000~~chr21:43175000-43200000,
chr21:42900000-42925000~~chr21:43200000-43225000,
chr21:42900000-42925000~~chr21:43300000-43325000,
chr21:42900000-42925000~~chr21:43325000-43350000,
chr21:42900000-42925000~~chr21:43350000-43375000,
chr21:42900000-42925000~~chr21:43600000-43625000,
chr21:42900000-42925000~~chr21:43625000-43650000,
chr21:42900000-42925000~~chr21:43650000-43675000,
chr21:6425000-6450000~~chr21:42900000-42925000,
chr21:6475000-6500000~~chr21:42875000-42900000,
chr21:6475000-6500000~~chr21:42900000-42925000,