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Basic information

CohesinDB ID: CDBP00420528

Locus: chr21-42898938-42900986

Data sourse: GSE67783, ENCSR153HNT, GSE86191

Cell type: K-562, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 83% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "4_Tx": 65%, "5_TxWk": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFIA, PGR, POU2F2, ZNF316, TBL1X, POU5F1, TOP2A, PAF1, ZFX, XBP1, GTF2B, WT1, ZBTB48, ZSCAN5A, FOXA1, ZNF574, DDX5, RBFOX2, HOXB13, TBP, PRDM10, ERG, RELA, ZNF384, MYC, NFIC, OSR2, SP140, NFIB, ARNT, NKX2-1, ZNF708, GABPA, TP63, NRIP1, GATA1, ZNF143, SNRNP70, DNMT3B, SUPT5H, MED1, ZNF467, SP2, NR3C1, NCOA3, EZH2, ESR1, OCA2, GRHL2, USF2, CTCF, RBM22, BCL11A, AR, PAX8, HDAC2, REST, BRD4, MAZ, STAG1, TFAP2C, EED

Target gene symbol (double-evidenced CRMs): U2AF1,SUMO3,RRP1B,DNMT3L,RRP1,CSTB,CBS,HSF2BP,PKNOX1,UBE2G2,NDUFV3

Function elements

Human SNPs: .

Number of somatic mutations (coding): 8

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000160194, ENSG00000160199, ENSG00000160200, ENSG00000160201, ENSG00000160207, ENSG00000160208, ENSG00000160213, ENSG00000160214, ENSG00000142182, ENSG00000184787, ENSG00000184900,

eachgene

Deatailed information for cohesin site CDBP00420528