- Basic information
- CohesinDB ID: CDBP00420529
- Locus: chr21-42901231-42902142
-
Data sourse: GSE67783, ENCSR153HNT, GSE86191
-
Cell type: K-562, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
83% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"4_Tx": 60%,
"5_TxWk": 40%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFIA, PGR, POU2F2, ZNF316, TBL1X, POU5F1, TOP2A, PAF1, ZFX, XBP1, GTF2B, WT1, ZBTB48, ZSCAN5A, FOXA1, ZNF574, DDX5, RBFOX2, HOXB13, TBP, PRDM10, ERG, RELA, ZNF384, MYC, NFIC, OSR2, SP140, NFIB, ARNT, NKX2-1, ZNF708, GABPA, TP63, NRIP1, GATA1, ZNF143, SNRNP70, DNMT3B, SUPT5H, MED1, ZNF467, SP2, NR3C1, NCOA3, EZH2, ESR1, OCA2, GRHL2, USF2, CTCF, RBM22, BCL11A, AR, PAX8, HDAC2, REST, BRD4, MAZ, STAG1, TFAP2C, EED
- Target gene symbol (double-evidenced CRMs): HSF2BP,CBS,PKNOX1,NDUFV3,RRP1B,U2AF1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 4
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000160194,
ENSG00000160199,
ENSG00000160200,
ENSG00000160201,
ENSG00000160207,
ENSG00000160208,
- Related loop:
chr21:42875000-42900000~~chr21:43175000-43200000,
chr21:42875000-42900000~~chr21:43325000-43350000,
chr21:42875000-42900000~~chr21:43350000-43375000,
chr21:42875000-42900000~~chr21:43625000-43650000,
chr21:42875000-42900000~~chr21:43650000-43675000,
chr21:42875000-42900000~~chr21:43775000-43800000,
chr21:42875000-42900000~~chr21:44250000-44275000,
chr21:42875000-42900000~~chr21:44800000-44825000,
chr21:42900000-42925000~~chr21:43000000-43025000,
chr21:42900000-42925000~~chr21:43025000-43050000,
chr21:42900000-42925000~~chr21:43100000-43125000,
chr21:42900000-42925000~~chr21:43175000-43200000,
chr21:42900000-42925000~~chr21:43200000-43225000,
chr21:42900000-42925000~~chr21:43300000-43325000,
chr21:42900000-42925000~~chr21:43325000-43350000,
chr21:42900000-42925000~~chr21:43350000-43375000,
chr21:42900000-42925000~~chr21:43600000-43625000,
chr21:42900000-42925000~~chr21:43625000-43650000,
chr21:42900000-42925000~~chr21:43650000-43675000,
chr21:6425000-6450000~~chr21:42900000-42925000,
chr21:6475000-6500000~~chr21:42875000-42900000,
chr21:6475000-6500000~~chr21:42900000-42925000,