Browse_each

Basic information

CohesinDB ID: CDBP00420530

Locus: chr21-42903879-42905128

Data sourse: GSE67783, ENCSR000BKV, GSE86191, GSE129526, ENCSR153HNT, GSE25021, GSE50893

Cell type: MCF-7, HCT-116, K-562, HSPC, GM18486

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 83% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "4_Tx": 79%, "5_TxWk": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, JARID2, TRP47, POU2F2, CHD8, FOXA2, AGO1, MYCN, RUNX1T1, ZSCAN5D, ZFX, PAF1, XBP1, ZMYND11, DUX4, ZBTB48, WT1, STAT1, ZBTB33, RBFOX2, YY1, RELA, ZNF384, OGG1, ATF3, MYC, EZH1, GATA4, PRDM1, ARNT, SP140, GRHL3, POU5F1, ATF4, STAT3, CHD1, AGO2, CDK8, DNMT3B, GATA1, ZNF143, SUPT5H, NCOA3, ZNF121, SMAD5, ESR1, TP53, KLF9, CTCF, RBM22, ZHX2, SPI1, AR, PAX8, HDAC2, EGR1, FLI1, ASH2L, HSF1, MYNN, BRD4, FOXP1, MAZ, AATF, SMC3, STAG1, AHR, EED

Target gene symbol (double-evidenced CRMs): HSF2BP,CBS,U2AF1,PKNOX1,RRP1B,NDUFV3

Function elements

Human SNPs: .

Number of somatic mutations (coding): 126

Number of somatic mutations (non-coding): 58

Related genes and loops

Related gene: ENSG00000160194, ENSG00000160199, ENSG00000160200, ENSG00000160201, ENSG00000160207, ENSG00000160208,

eachgene

Deatailed information for cohesin site CDBP00420530