Browse_each

Basic information

CohesinDB ID: CDBP00420531

Locus: chr21-42905606-42906786

Data sourse: GSE132649, GSE67783, ENCSR153HNT, GSE86191

Cell type: K-562, T-47D, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 83% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "4_Tx": 74%, "5_TxWk": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFIA, POU2F2, CHD8, ZSCAN5D, ZNF263, POU5F1, E2F8, ZFX, ZMYND11, XBP1, ZBTB48, WT1, ZSCAN5A, ZNF770, ZBTB33, DDX5, RBFOX2, HOXB13, TWIST1, FOXO3, ZKSCAN1, RELA, HDGF, NEUROD1, ETS1, NFIC, ZNF362, GRHL3, ARNT, NFIB, RXRA, ZNF48, GABPA, SP2, SUPT5H, CHD1, MITF, DNMT3B, ZNF143, CEBPB, TEAD3, NCOA3, MYB, EZH2, ESR1, OCA2, NCOA1, ZIK1, CTCF, TCF12, RBM22, AR, ZBTB26, HSF1, HCFC1, BRD4, ZNF554, STAG1, EED

Target gene symbol (double-evidenced CRMs): RRP1B,PKNOX1,HSF2BP,NDUFV3,CBS,U2AF1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 18

Number of somatic mutations (non-coding): 9

Related genes and loops

Related gene: ENSG00000160194, ENSG00000160199, ENSG00000160200, ENSG00000160201, ENSG00000160207, ENSG00000160208,

eachgene

Deatailed information for cohesin site CDBP00420531