- Basic information
- CohesinDB ID: CDBP00420536
- Locus: chr21-42915076-42915684
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Data sourse: GSE67783, GSE86191, GSE105028, GSE206145, ENCSR153HNT, GSE165895
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Cell type: RPE, HCT-116, H9-hESC, K-562, HSPC, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
83% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 76%,
"15_Quies": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, XBP1, FOXA1, RBFOX2, LEO1, HDGF, ZFP64, ZNF362, ZNF322, CBFB, ZNF189, MECOM, TP63, KLF5, ZNF121, ZNF573, RBM39, SMAD5, ESR1, OCA2, TP73, ZBTB49, CTCF, JUN, PAX8, ZNF528, TEAD4, TFAP2C, EED, GLIS1, CDK9-HEXIM1, POU2F2, CHD8, ZSCAN5D, ZNF263, MYCN, RUNX1T1, TOP2A, ZSCAN21, ZBTB17, DUX4, ZBTB48, ZSCAN5A, ZNF563, DDX5, ERG2, ERG, MYC, SMARCA4, APC, NKX3-1, ZNF667, HNRNPH1, EZH2, ZHX2, SPI1, ZNF664, GATA2, SIX2, FLI1, ZNF766, NCOA2, RUNX1, BCL6, SMC1A, ZFX, ERG3, PRDM10, NSD2, ZNF384, ZNF133, RUNX2, CDK6, OSR2, PBX4, ARNT, ZNF48, SUPT5H, CDK8, MED1, TEAD3, SUPT16H, ZNF22, RBM22, BCL11A, NIPBL, ARID1A, FOXP1, SMC3, STAG1, MLLT1, ZNF394, TRP47, TBL1X, MTA3, PAF1, E2F8, NFATC1, WT1, MEF2C, HOXB13, MPHOSPH8, YY1, RELA, NEUROD1, ZNF510, SP140, MAX, AGO2, NCOA3, KDM5B, TP53, PHOX2B, AR, ZBTB42, MYNN, NCOR1, BRD4, ILF3, MAZ
- Target gene symbol (double-evidenced CRMs): RRP1B,U2AF1,PKNOX1,HSF2BP,NDUFV3,CBS
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 5
- Related genes and loops
- Related gene:
ENSG00000160194,
ENSG00000160199,
ENSG00000160200,
ENSG00000160201,
ENSG00000160207,
ENSG00000160208,
- Related loop:
chr21:42900000-42925000~~chr21:43000000-43025000,
chr21:42900000-42925000~~chr21:43025000-43050000,
chr21:42900000-42925000~~chr21:43100000-43125000,
chr21:42900000-42925000~~chr21:43175000-43200000,
chr21:42900000-42925000~~chr21:43200000-43225000,
chr21:42900000-42925000~~chr21:43300000-43325000,
chr21:42900000-42925000~~chr21:43325000-43350000,
chr21:42900000-42925000~~chr21:43350000-43375000,
chr21:42900000-42925000~~chr21:43600000-43625000,
chr21:42900000-42925000~~chr21:43625000-43650000,
chr21:42900000-42925000~~chr21:43650000-43675000,
chr21:6425000-6450000~~chr21:42900000-42925000,
chr21:6475000-6500000~~chr21:42900000-42925000,