- Basic information
- CohesinDB ID: CDBP00420538
- Locus: chr21-42917709-42919392
-
Data sourse: GSE67783, GSE86191, GSE126634, ENCSR153HNT, GSE165895
-
Cell type: HCT-116, HSPC, K-562, HAP1, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
83% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"5_TxWk": 64%,
"15_Quies": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RUNX2, PAX5, NKX2-1, FOXA1, MAX, RBM22, TFAP2C
- Target gene symbol (double-evidenced CRMs): U2AF1,PKNOX1,CBS,NDUFV3,RRP1B,HSF2BP
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 3
- Related genes and loops
- Related gene:
ENSG00000160194,
ENSG00000160199,
ENSG00000160200,
ENSG00000160201,
ENSG00000160207,
ENSG00000160208,
- Related loop:
chr21:42900000-42925000~~chr21:43000000-43025000,
chr21:42900000-42925000~~chr21:43025000-43050000,
chr21:42900000-42925000~~chr21:43100000-43125000,
chr21:42900000-42925000~~chr21:43175000-43200000,
chr21:42900000-42925000~~chr21:43200000-43225000,
chr21:42900000-42925000~~chr21:43300000-43325000,
chr21:42900000-42925000~~chr21:43325000-43350000,
chr21:42900000-42925000~~chr21:43350000-43375000,
chr21:42900000-42925000~~chr21:43600000-43625000,
chr21:42900000-42925000~~chr21:43625000-43650000,
chr21:42900000-42925000~~chr21:43650000-43675000,
chr21:42922609-42925287~~chr21:43644896-43647868,
chr21:42922692-42925178~~chr21:43644727-43647870,
chr21:42922930-42925162~~chr21:43644933-43647734,
chr21:42922962-42925091~~chr21:43644228-43647626,
chr21:42922972-42925217~~chr21:43644939-43647696,
chr21:42923020-42925261~~chr21:43644178-43647643,
chr21:6425000-6450000~~chr21:42900000-42925000,
chr21:6475000-6500000~~chr21:42900000-42925000,