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Basic information

CohesinDB ID: CDBP00420539

Locus: chr21-42919813-42921376

Data sourse: GSE206145-GSE177045, GSE67783, GSE86191, GSE85526, GSE206145-NatGen2015, ENCSR153HNT, ENCSR703TNG

Cell type: MCF-7, Fibroblast, HCT-116, HEKn, K-562, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.933

Subunit: Mau2,SA1,Rad21,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 83% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 66%, "15_Quies": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RELA, AR, CREBBP, NR3C1, PGR, GATAD2B, NKX2-2, NKX3-1, ZFX, LMO2, ESR1, PKNOX1, ZSCAN5A, GRHL2, NCOA2, NRIP1, PDX1

Target gene symbol (double-evidenced CRMs): U2AF1,PKNOX1,CBS,RRP1B,HSF2BP

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000160199, ENSG00000160200, ENSG00000160201, ENSG00000160207, ENSG00000160208,

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Deatailed information for cohesin site CDBP00420539